An Overview of TSE Diseases

DOI

10.2991/978-2-494069-89-3_190How to use a DOI?

Keywords

TSE disease; Misfolded; Prion protein; Detect; Therapeutics

Abstract

Prion disease is a sparse, life threatening, and unusually dramatic neurodegenerative disease. Although there is no radical cure for prion diseases, the diseases follow an apparent pathogenic mechanism. A single gene produces a single corresponding prion protein (pRP) that could potentially transform into the only disease-causing factor, a misfolded prion. The cellular prion protein PrP C is a small glycoprotein on the cellular surface whose roles is currently unknown. Besides that, it is a critical molecule associated with a school of neurodegenerative diseases known as infectious spongiform encephalopathies (also known as prion diseases). Currently, the definitive diagnosis of TSE is determined post-mortem and is difficult to detect in asymptomatic carriers of the disease. There is a greatneed for improved methods to detect TSE to improve the safety of food, drugs, and blood products.

Copyright

© 2022 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Houhua Hu
PY  - 2022
DA  - 2022/12/30
TI  - An Overview of TSE Diseases
BT  - Proceedings of the 2022 5th International Conference on Humanities Education and Social Sciences (ICHESS 2022)
PB  - Atlantis Press
SP  - 1656
EP  - 1662
SN  - 2352-5398
UR  - https://doi.org/10.2991/978-2-494069-89-3_190
DO  - 10.2991/978-2-494069-89-3_190
ID  - Hu2022
ER  -