The Risk Factors and Causes for Alzheimer’s Disease

DOI

10.2991/assehr.k.220504.160How to use a DOI?

Keywords

Alzheimer’s disease; Epidemiology; Genes; Amyloid; Tau

Abstract

Alzheimer’s disease, the most common neurodegenerative disease, is categorised by two hallmarks, plaques and tangles, which are formed by accumulated Amyloid-b and hyperphosphorylated tau proteins. However, there is still no treatment or cure for this expensive and lethal disease. Some drugs targeting Ab and tau proteins theoretically should work, but all fail in the phase 3 trial due to the poor benefits and side effects. This review summarises the epidemiology, genetics, and biochemistry of Alzheimer’s disease, showing that age is the main risk factor while the area, income, gender and the surrounding environment can also affect the chances of Alzheimer’s disease. In addition, the cause of Alzheimer’s disease can be explained by Ab and tau hypotheses and the genes related to it.

Copyright

© 2022 The Authors. Published by Atlantis Press SARL.

Open Access

This is an open access article distributed under the CC BY-NC 4.0 license.

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TY  - CONF
AU  - Youchong Zhang
PY  - 2022
DA  - 2022/06/01
TI  - The Risk Factors and Causes for Alzheimer’s Disease
BT  - Proceedings of the 2022 8th International Conference on Humanities and Social Science Research (ICHSSR 2022)
PB  - Atlantis Press
SP  - 872
EP  - 877
SN  - 2352-5398
UR  - https://doi.org/10.2991/assehr.k.220504.160
DO  - 10.2991/assehr.k.220504.160
ID  - Zhang2022
ER  -