In the field of science research and innovation, UK has always maintained world-class development level. UK government attaches great importance to science research management system development, including science research investment funds, science researchers educational funds and academic exchanges. The government aims to strengthen and maintain industrial advantage in the field of competitive technology in the UK. This paper summarizes UK public science research management mode, and take UK Research Councils (RCUK), Higher Education Funding Council (HEFCs) and other foundation organizations as examples to analysis institution and project funding system. Furthermore, it puts forward some suggestions for advancing management of research and development, improving research assessment exercise and promoting public research institutions reformation.