Synthesis of 3- morpholin-4-yl-1- (4-nitrophenyl) -5,6-dihydro -1H- pyridin-2-one
Linxiao Wang, Jianqiang Wang, Shan Xu, Jielian Wu, Qidong Tang, Pengwu Zheng
Available Online March 2016.
- https://doi.org/10.2991/icmmct-16.2016.149How to use a DOI?
- 3-Morpholin-4-yl-1-(4-nitrophenyl)-5,6-dihydro-1H-pyridin-2-one, Synthesis , Cyclopentanone oxime
- 3-Morpholin-4-yl-1-(4-nitrophenyl)-5,6-dihydro-1H-pyridin-2-one (1) is an important intermediate for the synthesis of many biologically active compounds. It was synthesized from cyclopentanone oxime (7) and 1-fluoro-4-nitrobenzene through three steps including rearrangement Reaction, condensation and nucleophilic substitution reaction. The structure of the target compound 1 was confirmed by 1H NMR and MS spectrum.
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- This is an open access article distributed under the CC BY-NC license.
Cite this article
TY - CONF AU - Linxiao Wang AU - Jianqiang Wang AU - Shan Xu AU - Jielian Wu AU - Qidong Tang AU - Pengwu Zheng PY - 2016/03 DA - 2016/03 TI - Synthesis of 3- morpholin-4-yl-1- (4-nitrophenyl) -5,6-dihydro -1H- pyridin-2-one BT - Proceedings of the 2016 4th International Conference on Machinery, Materials and Computing Technology PB - Atlantis Press SP - 765 EP - 768 SN - 2352-5401 UR - https://doi.org/10.2991/icmmct-16.2016.149 DO - https://doi.org/10.2991/icmmct-16.2016.149 ID - Wang2016/03 ER -