Proceedings of the 2016 4th International Conference on Machinery, Materials and Computing Technology

Synthesis of 3- morpholin-4-yl-1- (4-nitrophenyl) -5,6-dihydro -1H- pyridin-2-one

Authors
Linxiao Wang, Jianqiang Wang, Shan Xu, Jielian Wu, Qidong Tang, Pengwu Zheng
Corresponding Author
Linxiao Wang
Available Online March 2016.
DOI
https://doi.org/10.2991/icmmct-16.2016.149How to use a DOI?
Keywords
3-Morpholin-4-yl-1-(4-nitrophenyl)-5,6-dihydro-1H-pyridin-2-one, Synthesis , Cyclopentanone oxime
Abstract
3-Morpholin-4-yl-1-(4-nitrophenyl)-5,6-dihydro-1H-pyridin-2-one (1) is an important intermediate for the synthesis of many biologically active compounds. It was synthesized from cyclopentanone oxime (7) and 1-fluoro-4-nitrobenzene through three steps including rearrangement Reaction, condensation and nucleophilic substitution reaction. The structure of the target compound 1 was confirmed by 1H NMR and MS spectrum.
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This is an open access article distributed under the CC BY-NC license.

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Volume Title
Proceedings of the 2016 4th International Conference on Machinery, Materials and Computing Technology
Series
Advances in Engineering Research
Publication Date
March 2016
ISBN
978-94-6252-165-0
ISSN
2352-5401
DOI
https://doi.org/10.2991/icmmct-16.2016.149How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Linxiao Wang
AU  - Jianqiang Wang
AU  - Shan Xu
AU  - Jielian Wu
AU  - Qidong Tang
AU  - Pengwu Zheng
PY  - 2016/03
DA  - 2016/03
TI  - Synthesis of 3- morpholin-4-yl-1- (4-nitrophenyl) -5,6-dihydro -1H- pyridin-2-one
BT  - Proceedings of the 2016 4th International Conference on Machinery, Materials and Computing Technology
PB  - Atlantis Press
SP  - 765
EP  - 768
SN  - 2352-5401
UR  - https://doi.org/10.2991/icmmct-16.2016.149
DO  - https://doi.org/10.2991/icmmct-16.2016.149
ID  - Wang2016/03
ER  -