Study on preparation and properties of pH, temperature and ionic sensitive polyurethanes hydrogel

DOI

10.2991/icmse-15.2015.291How to use a DOI?

Keywords

polyurethane, hydrogel, swelling behavior, multiple-sensitive

Abstract

Polyurethane hydrogel(PUHG), which exhibits pH, temperature and ionic intensity sensitive, was synthesized by using the toluene diisocyanate(TDI), polyethylene glycol(PEG-6000), dimet hylol propionic acid(DMPA) and triethylene tetramine(TEFA).The effect of pH, temperature, ionic intensity and crosslinking agent on welling ratio of the PUHG was studied in detail . The result showed that the swelling ratio of PUHG decreased with the temperature increasing between 20 and 45 C but didn’t change after 45 C; in alkaline medium (pH=9), the swelling ratio of the PUHG was more than that of In acid medium (pH=4), which indicated it had a good sensitivity; the swelling ratio of PUHG decreased with ionic intensity increasing at a temperature and pH. The results of swelling dynamic indicated that PUHG can change reversibly well at different pH and temperature. So the PUHG is suitable for use in biomedical controlled delivery of medicines.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Xiaoli Zhang
AU  - Xiaoyang Guo
AU  - Heying Bian
PY  - 2015/12
DA  - 2015/12
TI  - Study on preparation and properties of pH, temperature and ionic sensitive polyurethanes hydrogel
BT  - Proceedings of the 2015 6th International Conference on Manufacturing Science and Engineering
PB  - Atlantis Press
SP  - 1607
EP  - 1610
SN  - 2352-5401
UR  - https://doi.org/10.2991/icmse-15.2015.291
DO  - 10.2991/icmse-15.2015.291
ID  - Zhang2015/12
ER  -