Expression of IL-1 on Mucosal Cavity's Chronic Inflammation after Provision of Clarias Batrachus Fish Oil
Theresia Indah Budhy, Istiati Istiati, Intan Vallentien Dwi Hariati
Theresia Indah Budhy
Available Online July 2017.
- https://doi.org/10.2991/icoh-17.2018.12How to use a DOI?
- Chronic inflammation, IL-1, Fish oil Clariasbatrachus
- Background. The presence of cell or tissue damage always followed byinflammatory reactions. Inflammatory process should not persist because it can interfere even inhibit regeneration. An increased circulation of IL-1, IL-6 and TNF-alpha happens in chronic inflammation. IL-1 is granulocytes chemoattractant and has function to localize inflammation. Overexpression of IL-1 can inhibit wound healing so it needs currative treatment to decrease IL-1's expression. Purpose. To know expression of IL-1 after provision of Clariasbatrachus fish oil. Methods. We have used the post test only design in this research. There have been 19 Rattusnovergicus as research samples and those were divided into 3 groups, group 1 as control, group 2 has given 10% fish oil and group 2 has given 5% fish oil. Chronic inflammation treated to all samples for three days. The group 1 and 2 given Clariasbatrachusfish oil on the third day. We did decapitation on the fourth day to perform Immunohistochemistrystaining. The data were tabulated and analyzed statistically used Oneway ANOVA.Result. Group 2 and 3 has lower IL-1 expression than Control group.There is significant difference between groups. Conclusion. Clariasbatrachus Fish oil can lowered IL-1 expression onmucosal cavity's chronic inflammation.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
Cite this article
TY - CONF AU - Theresia Indah Budhy AU - Istiati Istiati AU - Intan Vallentien Dwi Hariati PY - 2017/07 DA - 2017/07 TI - Expression of IL-1 on Mucosal Cavity's Chronic Inflammation after Provision of Clarias Batrachus Fish Oil BT - 1st International Conference in One Health (ICOH 2017) PB - Atlantis Press SN - 2468-5739 UR - https://doi.org/10.2991/icoh-17.2018.12 DO - https://doi.org/10.2991/icoh-17.2018.12 ID - Budhy2017/07 ER -