Bats As A Viral Reservoir: A Short Review Of Their Ecological Characters And Immune System
Desrayni Hanadhita, Aryani Sismin Satyaningtijas, Srihadi Agung Priyono
Available Online July 2017.
- https://doi.org/10.2991/icoh-17.2018.25How to use a DOI?
- chiropterans, reservoir, flying mammal, zoonosis, immunology
- Bats are reported as natural reservoir host of several viruses, many of which cause severe human disease. Infected bats usually do not show any clinical symptoms and persistently infected. Bats immunity against viruses is an evolutional process of self-defense created by ecological adaptation between host and pathogen. Bats have unique characters which support them as a viral reservoir, whereas RNA viruses which are commonly carried by bats take an advantage of these characteristics to survive. The role of bats as reservoirs is also supported by several differences of immune system than other mammals. Several studies on molecular factors of bats immune system lead to a hypothesis that bats are able to control viral replication very early in the immune response through innate antiviral mechanism. However, to complete understanding of the nature of immune responses of bats to the virus still needs a lot of study. Advance technology on molecular techniques revealed the immune factors and provided numerous data about molecular factors in bat immunity, however comprehensive studies about morphology of bats immune organs are still lacking. One of the important immune organs which have functional variations due to their structural differences between species is the spleen, which will be our main focus of study in the future. We hope that the result of our study will be able to provide the database on the morphology and physiology of bat spleen and give better understanding on bats immune system.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
Cite this article
TY - CONF AU - Desrayni Hanadhita AU - Aryani Sismin Satyaningtijas AU - Srihadi Agung Priyono PY - 2017/07 DA - 2017/07 TI - Bats As A Viral Reservoir: A Short Review Of Their Ecological Characters And Immune System BT - 1st International Conference in One Health (ICOH 2017) PB - Atlantis Press SN - 2468-5739 UR - https://doi.org/10.2991/icoh-17.2018.25 DO - https://doi.org/10.2991/icoh-17.2018.25 ID - Hanadhita2017/07 ER -