Proceedings of the 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020)

Evaluation of Potential Drug-Drug Interactions in Hypercholesterolemia Patients at Teaching Hospital Surabaya

Authors
Ana Khusnul Faizah, Nani Wijayanti Dyah Nurrahman
Corresponding Author
Ana Khusnul Faizah
Available Online 16 January 2021.
DOI
10.2991/ahsr.k.210115.064How to use a DOI?
Keywords
Drug interactions, pDDIs, Pharmacokinetic, Pharmacodynamics, Hypercholesterolemia
Abstract

Drug-drug interactions increase the effectiveness of therapy but can also have undesirable effects on toxicity. A pharmacist has the responsibility to prevent the undesirable effect of drug-drug interactions. The purpose of this study was to evaluate the potential drug-drug interactions in hypercholesterolemia patients at Teaching Hospital Surabaya. This study was conducted with a prospective method for a month. We obtained 54 patients and identified 45 patients that have potential drug-drug interactions. The total potential drug-drug interactions were 101. The severity of potential drug-drug interactions is serious (24,7%) and moderate (75,3%). Based on the mechanism action of drug interactions are pharmacodynamics (59,4%), pharmacokinetics (32,7%), and unknown (7,9%). The role of the pharmacist in providing safe, effective and rational drug therapy can be done by either identifying drug interactions, prevent and minimize the negative effect of drug interactions.

Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Download article (PDF)

Volume Title
Proceedings of the 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020)
Series
Advances in Health Sciences Research
Publication Date
16 January 2021
ISBN
978-94-6239-315-8
ISSN
2468-5739
DOI
10.2991/ahsr.k.210115.064How to use a DOI?
Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Ana Khusnul Faizah
AU  - Nani Wijayanti Dyah Nurrahman
PY  - 2021
DA  - 2021/01/16
TI  - Evaluation of Potential Drug-Drug Interactions in Hypercholesterolemia Patients at Teaching Hospital Surabaya
BT  - Proceedings of the 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020)
PB  - Atlantis Press
SP  - 302
EP  - 304
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.210115.064
DO  - 10.2991/ahsr.k.210115.064
ID  - Faizah2021
ER  -