Proceedings of the 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020)

The Effect of Moringa Oleifera Leaf Extract on Mean Platelet Volume and Neutrophil-to-Lymphocyte Ratio in Autoimmune Patients

Authors
Nurhasan Agung Prabowo, Arief Nurudhin, Ayuningdyah Chitra Buanantri
Corresponding Author
Nurhasan Agung Prabowo
Available Online 23 January 2021.
DOI
https://doi.org/10.2991/ahsr.k.210115.118How to use a DOI?
Keywords
Moringa oleifera extract, mean platelet volume, neutrophil-to-lymphocyte ratio, autoimmune patients
Abstract

Background: Moringa oleifera is one of the promising novel treatments in autoimmune diseases through anti-inflammation and immunosuppression. Mean platelet volume and neutrophil-to-lymphocyte ratio are used to measure the degree of inflammation. This study aimed to identify the effect of Moringa oleifera leaf extract on the mean platelet volume and neutrophil-lymphocyte ratio in autoimmune patients. Research methods: This experimental study was conducted on 30 autoimmune patients consisting of 28 lupus patients and 2 rheumatoid arthritis patients of the rheumatology clinic at Moewardi General Hospital in January-March 2019. The patient was grouped into two, the treatment and control groups. The patients were in the treatment group received 2 grams of Moringa oleifera leaf extract per day, while those in the control group received a placebo. The study was conducted for 4 weeks, concluded with an evaluation. MPV (mean platelet volume) and NLR (neutrophil-to-lymphocyte ratio) examination used a haemocytometer. Statistical analysis was performed using paired T-test and independent T-test. The p-value was considered significant when p < 0.05. Results: The results showed that Moringa oleifera leaf extract decreases MPV (delta MPV = 4.141; r = 0.656; p- value = 0.02) and Neutrophil-to- lymphocyte ratio (delta NLR = 4.1391; r 0.489; p-value = 0.04). Conclusion: The study revealed that Moringa oleifera leaf extract decreased mean platelet volume and neutrophil-to-lymphocyte ratio in autoimmune patients.

Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020)
Series
Advances in Health Sciences Research
Publication Date
23 January 2021
ISBN
978-94-6239-315-8
ISSN
2468-5739
DOI
https://doi.org/10.2991/ahsr.k.210115.118How to use a DOI?
Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Nurhasan Agung Prabowo
AU  - Arief Nurudhin
AU  - Ayuningdyah Chitra Buanantri
PY  - 2021
DA  - 2021/01/23
TI  - The Effect of Moringa Oleifera Leaf Extract on Mean Platelet Volume and Neutrophil-to-Lymphocyte Ratio in Autoimmune Patients
BT  - Proceedings of the 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020)
PB  - Atlantis Press
SP  - 625
EP  - 629
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.210115.118
DO  - https://doi.org/10.2991/ahsr.k.210115.118
ID  - Prabowo2021
ER  -