Supramolecular Compounds of β-cyclodextrins as a Material for the Pharmaceutical Industry
- 10.2991/isees-19.2019.37How to use a DOI?
- cyclodextrin; amino acids; inclusion complexes; complexes of amino acids with rare-earth elements.
The binary systems Eu(L)3(ClO4)3∙2H2O and ternary systems EuL3(CD)3∙2H2O were synthesized. The structural features of the systems were analyzed. The composition and structure of the synthesized complex compounds were studied by NMR spectroscopy, IR spectroscopy, X-ray phase analysis, thermal analysis, and luminescence analysis. It was revealed that during formation of the ternary system, the amino acid enters the cyclodextrin cavity and is preserved by hydrogen bonds; coordination with Eu3 + is due to the carboxyl group (COO-), which is outside the cyclodextrin cavity. It was assumed that the spatial structure of the ternary system includes metal, amino acid, and β – cyclodextrin, where the ion of europium is used as a metal. It is used to track drug transportation in the biological systems.
- © 2019, the Authors. Published by Atlantis Press.
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- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - E.L. Isaeva AU - Khasaeva S.S. Khasaeva AU - E.R. Aslambekova AU - V.T. Panyushkin PY - 2019/08 DA - 2019/08 TI - Supramolecular Compounds of β-cyclodextrins as a Material for the Pharmaceutical Industry BT - Proceedings of the International Symposium "Engineering and Earth Sciences: Applied and Fundamental Research" dedicated to the 85th anniversary of H.I. Ibragimov (ISEES 2019) PB - Atlantis Press SP - 638 EP - 645 SN - 2590-3217 UR - https://doi.org/10.2991/isees-19.2019.37 DO - 10.2991/isees-19.2019.37 ID - Isaeva2019/08 ER -