Antiacne Compound from the Methanolic Extract of Hyptis (Hyptis capitata) Roots
- 10.2991/absr.k.210408.045How to use a DOI?
- Antiacnce, Methanolic extract, Hyptis capitata, Maceration
In the search of the antiacne agent from tropical medicinal plants, the methanolic extract of Hyptis capitata root was subjected to antiacne assay guided isolation of active compound. Extraction was conducted by maceration using methanol. The methanol extract was separated by column chromatography assisted by thin-layer chromatography to obtain active compounds. Antiacne activity against Propionibacterium acnes was analyzed using agar diffusion method at a concentration of 200 μg/well with chloramphenicol as a positive control. Column chromatography of methanol extract gave five active fractions, in which fractions AH1 and AH2 to be the strongest by 85% and 82% inhibition respectively. Fraction AH1 was then chromatographed on silica gel column to obtain 16 subfractions. The active fractions isolated from H. capitata have the potential to be developed as a natural antiacne. Further purification, identification, and characterization of the active compounds would be our priority in future studies.
- © 2021, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Rahmini AU - Irawan Wijaya Kusuma AU - Cita Tri Murni Andayati AU - Dedi Satria AU - Yhiya Amen AU - Kuniyoshi Shimizu PY - 2021 DA - 2021/04/10 TI - Antiacne Compound from the Methanolic Extract of Hyptis (Hyptis capitata) Roots BT - Proceedings of the Joint Symposium on Tropical Studies (JSTS-19) PB - Atlantis Press SP - 274 EP - 276 SN - 2468-5747 UR - https://doi.org/10.2991/absr.k.210408.045 DO - 10.2991/absr.k.210408.045 ID - 2021 ER -