Proceedings of the 1st Lawang Sewu International Symposium 2022 on Health Sciences (LSISHS 2022)

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The Effectiveness of Galenic Cream of Seromucoid of Snail and Chitosan for Chronic Wound Treatment

Authors
Agnes Sri Harti1, *, Rahajeng Putriningrum2, Joko Santoso3, Sutiyo Dani Saputro1, Saelan Saelan1, Yusup Subagio Sutanto4
1Departement of Nursing, Kusuma Husada University of Surakarta, Surakarta, 57127, Indonesia
2Midwife Professional Study Program, Faculty of Health Sciences, Kusuma Husada University Surakarta, Surakarta, 57127, Indonesia
3Department of Pharmacy, Faculty of Health Sciences, Kusuma Husada University of Surakarta, Surakarta, 57127, Indonesia
4Pulmonary Disease Study Program, Faculty of Medicine, Sebelas Maret University of Surakarta, Surakarta, 57126, Indonesia
*Corresponding author. Email: agnessriharti168@gmail.com
Corresponding Author
Agnes Sri Harti
Available Online 19 April 2023.
DOI
10.2991/978-94-6463-132-6_18How to use a DOI?
Keywords
Snail Seromucoid; Chitosan; Galenic; Cream; Chronic Wound
Abstract

Background: A wound is a form of tissue damage to the skin caused by physical, chemical, and physiological conditions. Treatment of chronic wounds takes a relatively long time so a wound care process or wound management using traditional or modern medical therapy is needed. The development of material-based galenic formulations containing bioactive compounds which can be used for wound care management.

Aim: This research was to test and analyze the effectiveness galenic cream preparations of snail seromucoid and chitosan for wound care in vitro.

Methods: The method was based on the experimental design with the research stages covering bioformulation of galenic cream preparations of snail seromucoid and chitosan as well as testing the quality of galenic preparations physically, chemically, and microbiologically. Analysis of observational data was statistically tested using the One Way Anova.

Results: Bioformulation of seromucoid galenic cream 2.5% and chitosan 2.5% and their combination ratio (1:1), (1:2); (2:1) according to the requirements of BPOM No. 32 of 2019, it eligible the requirements for the quality test of cream preparations in a physicochemical manner including pH, antioxidant activity, dispersion, and adhesion and microbiologically includes Total Plate Number, Yeast Mold Number, and no microbial pathogens Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans.

Conclusion: Preparation of seromucoid cream and chitosan and their combination ratio (1:1), (1:2); (2:1) can be formulated into galenic cream preparations that can be applied for the treatment of chronic wounds.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 1st Lawang Sewu International Symposium 2022 on Health Sciences (LSISHS 2022)
Series
Advances in Health Sciences Research
Publication Date
19 April 2023
ISBN
10.2991/978-94-6463-132-6_18
ISSN
2468-5739
DOI
10.2991/978-94-6463-132-6_18How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Agnes Sri Harti
AU  - Rahajeng Putriningrum
AU  - Joko Santoso
AU  - Sutiyo Dani Saputro
AU  - Saelan Saelan
AU  - Yusup Subagio Sutanto
PY  - 2023
DA  - 2023/04/19
TI  - The Effectiveness of Galenic Cream of Seromucoid of Snail and Chitosan for Chronic Wound Treatment
BT  - Proceedings of the 1st Lawang Sewu International Symposium 2022 on Health Sciences (LSISHS 2022)
PB  - Atlantis Press
SP  - 146
EP  - 157
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-132-6_18
DO  - 10.2991/978-94-6463-132-6_18
ID  - Harti2023
ER  -