Proceedings of the 2018 8th International Conference on Management, Education and Information (MEICI 2018)

Research Progress of IL-33/ST2 Signaling Pathway in Cardiovascular Disease

Authors
Yang Wang, Bin Wang
Corresponding Author
Bin Wang
Available Online December 2018.
DOI
https://doi.org/10.2991/meici-18.2018.98How to use a DOI?
Keywords
Interleukin-33; ST2; Atherosclerosis; Heart failure; Myocardial infarction
Abstract

Soluble ST2 (sST2) is a protein of interleukin-1 (IL-1) receptor family, IL-33 is the special ligand of ST2, IL-33/ST2 signaling has a significantly effect in the inflammation and immunology diseases. It certified that ST2 can be secreted by the myocardial cells on the mechanical overload, and it can inhibit the anti-Hypertrophy and anti-fibrosis of IL-33, can induce the cardiac remodeling. New researches indict that ST2 effects on the process of atherosclerotic and is associated with incident hypertension. Higher sST2 is related to disease activity and adverse in coronary artery disease and heart failure. Aldosterone receptor antagonist plays an important role in the IL-33/ST2 pathway.

Copyright
© 2018, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2018 8th International Conference on Management, Education and Information (MEICI 2018)
Series
Advances in Intelligent Systems Research
Publication Date
December 2018
ISBN
978-94-6252-640-2
ISSN
1951-6851
DOI
https://doi.org/10.2991/meici-18.2018.98How to use a DOI?
Copyright
© 2018, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Yang Wang
AU  - Bin Wang
PY  - 2018/12
DA  - 2018/12
TI  - Research Progress of IL-33/ST2 Signaling Pathway in Cardiovascular Disease
BT  - Proceedings of the 2018 8th International Conference on Management, Education and Information (MEICI 2018)
PB  - Atlantis Press
SP  - 495
EP  - 499
SN  - 1951-6851
UR  - https://doi.org/10.2991/meici-18.2018.98
DO  - https://doi.org/10.2991/meici-18.2018.98
ID  - Wang2018/12
ER  -