Research on the Advances in the Application of Superparamagnetic Iron Oxide Nanoparticles in Targeted Diagnosis and Treatment in Pancreatic Cancer

DOI

10.2991/assehr.k.220105.152How to use a DOI?

Keywords

Superparamagnetic iron oxide nanoparticles; pancreatic cancer; magnetic heat therapy; magnetic resonance imaging (CT); Targeted drug carriers

Abstract

Superparamagnetic iron oxide nanoparticles (SPIO) are medical nanomaterials with the advantages of super-magnetic, surface modification and targetedness. At the same time, superparamagnetic iron oxide nanoparticles are beneficial for magnetic resonance imaging, but also can be combined with photodynamic therapy, photothermal therapy and magnetic heat therapy to treat tumors in the human body. Pancreatic cancer can be treated with superparamagnetic iron oxide nanoparticles. Pancreatic cancer is the “king of cancer” in the field of oncology, one of the worst malignant tumors in prognosis. Superparamagnetic iron oxide nanoparticles can properly solve the problem of low diagnosis and cure rate of pancreatic cancer. In this paper, the performance characteristics of SPIO and the application progress of SPIO in the diagnosis and treatment of pancreatic cancer are reviewed. In this paper, superparamagnetic iron oxide nanoparticles are studied by literature reference. While referring to relevant papers, the author also thinks and conceives. The main research directions are the preparation of SPIO, the advantages of targeted SPIO, the application of SPIO in magnetic resonance imaging, the principle of targeted drugs, and the principle of magnetic heat therapy for pancreatic cancer. The main results are as follows:1.Superparamagnetic iron oxide nanoparticles have many advantages, such as magnetic sensitivity, easy surface modification, targeting and high relaxation properties. 2. The preparation methods of SPIO are various, but the chemical coprecipitation method is widely used because of its simple operation, low cost and low requirements for the laboratory environment. 3. Active targeting SPIO is more effective in the diagnosis of pancreatic cancer. It can be used in magnetic resonance imaging to improve the clarity of imaging. 4. SPIO can be used to treat pancreatic cancer through targeted drugs and magnetic heat therapy.

Copyright

© 2022 The Authors. Published by Atlantis Press SARL.

Open Access

This is an open access article under the CC BY-NC license.

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TY  - CONF
AU  - Jiayi An
PY  - 2022
DA  - 2022/01/17
TI  - Research on the Advances in the Application of Superparamagnetic Iron Oxide Nanoparticles in Targeted Diagnosis and Treatment in Pancreatic Cancer
BT  - Proceedings of the 2021 International Conference on Social Development and Media Communication (SDMC 2021)
PB  - Atlantis Press
SP  - 828
EP  - 831
SN  - 2352-5398
UR  - https://doi.org/10.2991/assehr.k.220105.152
DO  - 10.2991/assehr.k.220105.152
ID  - An2022
ER  -