Analysis on Autophagy Dysfunction in Alzheimer’s Disease and Revelant Bioethic Issues in Its Healthcare

DOI

10.2991/assehr.k.220701.051How to use a DOI?

Keywords

Lysosome; Beta-amyloid; Autophagy; Alzheimer’s disease; Bioethical issue

Abstract

Alzheimer’s disease is a common degenerative disease that manifests itself primarily as tau tangles and amyloid beta protein plaques. In the last five years, studies on lysosomes have sparked interest in autophagy and autophagic dysfunction, yet the specific role of autophagy in the pathogenesis of Alzheimer’s disease is still not particularly clear. This paper focuses on the mechanisms of autophagy and the role of autophagy in the pathogenesis of Alzheimer’s disease, while exploring the biosynthesis of lysosomes and identifying abnormal autophagy as a major cause of the development of Alzheimer’s disease. Finally, the paper discussed the bioethical issues and moral dilemmas that patients, family members, caregivers and clinicians may face in Alzheimer’s disease, while highlighting the importance of conducting predictive testing and maintaining patient autonomy.

Copyright

© 2022 The Authors. Published by Atlantis Press SARL.

Open Access

This is an open access article distributed under the CC BY-NC 4.0 license.

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TY  - CONF
AU  - Jiaze Gao
PY  - 2022
DA  - 2022/07/04
TI  - Analysis on Autophagy Dysfunction in Alzheimer’s Disease and Revelant Bioethic Issues in Its Healthcare
BT  - Proceedings of the 2022 International Conference on Science and Technology Ethics and Human Future (STEHF 2022)
PB  - Atlantis Press
SP  - 251
EP  - 254
SN  - 2352-5398
UR  - https://doi.org/10.2991/assehr.k.220701.051
DO  - 10.2991/assehr.k.220701.051
ID  - Gao2022
ER  -