2.6 Validation of the Measurement of Aortic Stiffness by the CARDIS Laser Doppler Vibrometer
- 10.2991/artres.k.191224.011How to use a DOI?
Purpose: There is a need for new tools to screen large populations for cardiovascular disease risk. The CARDIS consortium (European Union H2020 funding) developed an easy-to-use, non-contact device for measuring carotid to femoral pulse wave velocity (cfPWV). It consists in a laser doppler vibrometer (LDV), which measures skin vibrations induced by large artery pulses. Pulse waveforms can be tracked and transit time (TT) can be calculated. This study aimed at comparing LDV-cfPWV with the reference cfPWV measured by applanation tonometry (Sphygmocor).
Methods: We included 100 patients with mild to stage 3 hypertension, controlled or not. Reflective tapes were applied on the carotid and femoral arteries to measure LDV-cfPWV 4 times. TT was measured by the foot-to-foot method from the maximum of 2nd derivative using in-house algorithms not requiring ECG, and compared to Sphygmocor (3 acquisitions).
Results: LDV-cfPWV was obtained in 100% of patients. Mean age was 47 ± 19 (range 19–85). Hypertensives were well controlled (119/65 mmHg). Mean value of LDV-cfPWV was 6.9 ± 1.7 m/s, compared to 7.5 ± 1.7 m/s with Sphygmocor, bias 0.65 ± 1.27, R value 0.72 (Figure 1), which qualifies agreement as acceptable according to the guidelines from the ARTERY Society . Reproducibility was good with a median coefficient of variation of 5.6%. LDV-cfPWV showed similar associations with age and blood pressure than tonometry (r = 0.68, p < 0.001 and r = 0.44, p < 0.001, respectively).
Conclusion: Non-contact measurement of pulse wave velocity by laser doppler vibrometry is feasible, fast and easy to perform, and provides acceptable agreement with reference technique.
- © 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
- Open Access
- This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - JOUR AU - Louise Marais AU - Hakim Khettab AU - Yanlu Li AU - Patrick Segers AU - Roel Baets AU - Koen Reesink AU - Soren Aasmul AU - Mirko De Melis AU - Pierre Boutouyrie PY - 2020 DA - 2020/02/17 TI - 2.6 Validation of the Measurement of Aortic Stiffness by the CARDIS Laser Doppler Vibrometer JO - Artery Research SP - S15 EP - S15 VL - 25 IS - Supplement 1 SN - 1876-4401 UR - https://doi.org/10.2991/artres.k.191224.011 DO - 10.2991/artres.k.191224.011 ID - Marais2020 ER -