Artery Research

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Volume 25, Issue Supplement 1, December 2019, Pages S69 - S69

P26 Ascending Aorta Longitudinal Strain is not Altered in Bicuspid Aortic Valve Patients

Authors
Andrea Guala1, Lydia Dux-Santoy1, Gisela Teixido-Tura2, Aroa Ruiz-Muñoz1, Laura Madrenas1, Minerva Gandara1, Augusto Sao-Aviles1, Filipa Valente2, Laura Galian-Gay2, Laura Gutierrez2, Teresa Gonzalez-Alujas2, Ignacio Ferreira2, Arturo Evangelista1, Jose Rodriguez-Palomares2
1Vall d'Hebron Institute of Research, Barcelona, Spain
2Department of Cardiology, Vall d'Hebron Hospital, Barcelona, Spain
Available Online 17 February 2020.
DOI
10.2991/artres.k.191224.060How to use a DOI?
Abstract

Background: Impaired ascending aorta (AAo) longitudinal strain, a marker of AAo deformation due to aorto-ventricular mechanical interaction, is related to progressive dilation and aortic events in Marfan syndrome [1]. Whether the high prevalence of dilation in bicuspid aortic valve (BAV) is due to intrinsically-altered aortic wall properties [2] or hemodynamic [3] is widely-discussed [4]. Whether AAo longitudinal strain is altered in BAV patients has never been assessed.

Methods: One-hundred five BAV patients, 47 patients with AAo dilation and tricuspid aortic valve (TAV) and 31 healthy volunteers, free from previous cardiac/aortic surgery, dissection and moderate/severe valvular disease had cine MR images to compute AAo longitudinal strain [1].

Results: Compared to healthy volunteers, the 25 non-dilated (z-score < 2) BAV patients were older (p < 0.001), had higher systolic blood pressure (SBP, p = 0.001), clinically-meaningless (BAV z-score = 0.74 ± 1.1) larger AAo diameter (p < 0.001) and similar diastolic blood pressure (DBP), BSA, stroke volume and heart rate. AAo longitudinal strain was lower in non-dilated BAV compared to healthy volunteers (13.7 vs 10.3%, p = 0.008) but this difference was not significant after correction for age. Compared to dilated TAV, dilated BAV patients were younger (p < 0.001), had lower BSA (p = 0.010) and AAo diameter (p = 0.003), higher DBP (p = 0.032) and similar SBP, stroke volume and heart rate. AAo longitudinal strain was higher in dilated BAV compared to dilated TAV (10 vs 7.2%, p < 0.001) but this difference was not significant after correction for age, BSA and DBP.

Conclusion: AAo longitudinal strain is similar in BAV and TAV matched for aortic dilation.

Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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<Previous Article In Issue
Next Article In Issue>
Journal
Artery Research
Volume-Issue
25 - Supplement 1
Pages
S69 - S69
Publication Date
2020/02/17
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.2991/artres.k.191224.060How to use a DOI?
Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - JOUR
AU  - Andrea Guala
AU  - Lydia Dux-Santoy
AU  - Gisela Teixido-Tura
AU  - Aroa Ruiz-Muñoz
AU  - Laura Madrenas
AU  - Minerva Gandara
AU  - Augusto Sao-Aviles
AU  - Filipa Valente
AU  - Laura Galian-Gay
AU  - Laura Gutierrez
AU  - Teresa Gonzalez-Alujas
AU  - Ignacio Ferreira
AU  - Arturo Evangelista
AU  - Jose Rodriguez-Palomares
PY  - 2020
DA  - 2020/02/17
TI  - P26 Ascending Aorta Longitudinal Strain is not Altered in Bicuspid Aortic Valve Patients
JO  - Artery Research
SP  - S69
EP  - S69
VL  - 25
IS  - Supplement 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191224.060
DO  - 10.2991/artres.k.191224.060
ID  - Guala2020
ER  -