Artery Research

Volume 25, Issue Supplement 1, December 2019, Pages S163 - S163

P123 Beyond Diameters, Flow Hemodynamics Quantified by Magnetic Resonance Imaging to Help Characterizing Aneurysmal Aorta

Authors
Sophia Houriez—Gombaud-Saintonge1, 2, *, Ariel Pascaner3, Gilles Soulat4, Umit Gencer5, Thomas Dietenbeck6, Damian Craiem7, Emilie Bollache6, Yasmina Chenoune2, Elie Mousseaux4, Nadjia Kachenoura1
1Laboratoire d’Imagerie Biomédicale
2ESME Research Lab
3IMETTYB - Universidad Favaloro - CONICET, Buenos Aires, Argentina
4Hopital Européen Georges Pompidou, Paris, France
5Hôpital Européen Georges Pompidou, Paris, France
6Laboratoire d’Imagerie Biomédicale, Paris, France
7IMETTYB - Universidad Favaloro - CONICET, Buenos Aires, France
*Corresponding author. Email: sophia.houriezgombaudsaintonge@gmail.com
Corresponding Author
Sophia Houriez—Gombaud-Saintonge
Available Online 17 February 2020.
DOI
https://doi.org/10.2991/artres.k.191224.149How to use a DOI?
Abstract

Purpose: Referral to surgery in thoracic aortic aneurysms (TAA) is based on maximal diameter (Dmax) measured from imaging, which is known to have a high diagnosis failure rate. In addition to geometry, 4D flow MRI provides a comprehensive time-resolved flow imaging. Thus, our aim was to evaluate the ability of 4D flow MRI-derived quantitative flow indices to characterize TAA.

Methods: We studied 20 patients with TAA and tricuspid valve (TAVd, Dmax = 43 ± 5 mm, Age = 66 ± 14 years) and 56 healthy controls (YC: 30 subjects, Age = 36 ± 9 years ≤50 years, OC: 26 subjects, Age = 65 ± 9 years > 50 years). All underwent 4D flow MRI. After aortic segmentation, ascending aorta (AA) backward flow volume (VBF) was calculated in addition to maximal velocity jet angle and eccentricity (Ecc). Receiver operating characteristic analysis was performed to assess the ability of flow indices to characterize AA = dilation.

Results: While AA Dmax was 1.4-fold higher in TAVd than OC, VBF increased by 6.5 folds and Ecc and Angle varied by 1.3 to 1.7 folds between the two groups. Moreover, VBF changed by 12.7 folds between the aneurysmal AA as compared to TAVd descending aorta. Finally, VBF increased consistently with age in all controls and was able to detect AA dilation with a 0.98 accuracy.

Conclusion: AA backward flow quantified from 4D flow MRI outperformed the previously described indices such as flow eccentricity and angle in the characterization of thoracic aortic aneurysms.

Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal
Artery Research
Volume-Issue
25 - Supplement 1
Pages
S163 - S163
Publication Date
2020/02/17
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
https://doi.org/10.2991/artres.k.191224.149How to use a DOI?
Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Sophia Houriez—Gombaud-Saintonge
AU  - Ariel Pascaner
AU  - Gilles Soulat
AU  - Umit Gencer
AU  - Thomas Dietenbeck
AU  - Damian Craiem
AU  - Emilie Bollache
AU  - Yasmina Chenoune
AU  - Elie Mousseaux
AU  - Nadjia Kachenoura
PY  - 2020
DA  - 2020/02/17
TI  - P123 Beyond Diameters, Flow Hemodynamics Quantified by Magnetic Resonance Imaging to Help Characterizing Aneurysmal Aorta
JO  - Artery Research
SP  - S163
EP  - S163
VL  - 25
IS  - Supplement 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191224.149
DO  - https://doi.org/10.2991/artres.k.191224.149
ID  - Houriez—Gombaud-Saintonge2020
ER  -