Artery Research

Volume 2, Issue 2, May 2008, Pages 74 - 76

Agreement between carotid and radial augmentation index: Does medication status affect the relation?

Authors
Jun Sugawaraa, b, *, Hidehiko Komineb, Koichiro Hayashib, Mutsuko Yoshizawab, Takashi Yokoib, Seiji Maedac, Hirofumi Tanakaa
aCardiovascular Aging Research Laboratory, Department of Kinesiology and Health Education, University of Texas at Austin, 1 University Station, D3700 Austin, TX 78712-1204, USA
bInstitute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Ibaraki, Japan
cCenter for Advanced Research Alliance, University of Tsukuba, Ibaraki, Japan

Grant support: JSPS Postdoctoral Fellowships for Research Abroad (JS).

*Corresponding author. Cardiovascular Aging Research Laboratory, Department of Kinesiology and Health Education, University of Texas at Austin, 1 University Station, D3700 Austin, TX 78712-1204, USA. Tel.: +1 512 471 8594; fax: +1 512 471 0946. E-mail address: jun.sugawara@mail.utexas.edu (J. Sugawara).
Corresponding Author
Jun Sugawara
Received 20 December 2007, Revised 4 March 2008, Accepted 7 March 2008, Available Online 28 April 2008.
DOI
https://doi.org/10.1016/j.artres.2008.03.001How to use a DOI?
Keywords
Arterial stiffness; Blood pressure waveform; Applanation tonometry
Abstract

Central augmentation index (AI) is an index for arterial stiffness and wave reflection, but the measurement requires technical precision. We recently reported that AI obtained directly from radial arterial pressure waveforms (without using the general transfer function) could provide equivalent information to carotid AI in healthy adults. The aim of the present study was to determine whether such association would exist among patients on anti-hypertensive drugs. Forty-six hypertensive patients taking blood pressure lowering medications (62 ± 9 years, mean ± SD) and 78 age-matched apparently healthy adults (60 ± 9 years) were studied. Carotid and radial AI were obtained using arterial applanation tonometry, and radial AI was calculated using the equation [(second peak radial systolic pressure - diastolic pressure)/(first peak radial systolic pressure - diastolic pressure) × 100]. Radial AI was strongly and positively correlated with carotid AI in medicated patients (r = 0.73, P < 0.0001) as well as in healthy controls (r = 0.84, P < 0.0001). The Brand–Altman plot demonstrated that the difference and SD between carotid and radial AI were not different between medicated patients and healthy controls (61.8 ± 7.7 vs 63.0 ± 7.7%). These results suggest that radial AI may be able to provide qualitatively similar information to carotid AI even in patients on antihypertensive medications.

Copyright
© 2008 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

Download article (PDF)
View full text (HTML)

Journal
Artery Research
Volume-Issue
2 - 2
Pages
74 - 76
Publication Date
2008/04/28
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
https://doi.org/10.1016/j.artres.2008.03.001How to use a DOI?
Copyright
© 2008 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Jun Sugawara
AU  - Hidehiko Komine
AU  - Koichiro Hayashi
AU  - Mutsuko Yoshizawa
AU  - Takashi Yokoi
AU  - Seiji Maeda
AU  - Hirofumi Tanaka
PY  - 2008
DA  - 2008/04/28
TI  - Agreement between carotid and radial augmentation index: Does medication status affect the relation?☆
JO  - Artery Research
SP  - 74
EP  - 76
VL  - 2
IS  - 2
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2008.03.001
DO  - https://doi.org/10.1016/j.artres.2008.03.001
ID  - Sugawara2008
ER  -