P.43 The Association Between Early Vascular Aging and Cyclothymic Affective Temperament
- 10.2991/artres.k.201209.055How to use a DOI?
- Vascular age; affective temperaments
Objectives: Affective temperaments (depressive, anxious, irritable, hyperthymic, cyclothymic) are regarded as the biologically stable core of personality, and accumulating data implies their relationship with cardiovascular diseases. There are currently limited data on the association of affective temperaments and early vascular aging. The aim of our study was to assess the potential relationship of affective temperaments and vascular age, as assessed by coronary CT.
Methods: In our current cross-sectional study, 209 patients referred to coronary computed tomography angiography (CCTA) due to suspected coronary artery disease (CAD), were included. After the evaluation of medical history and demographic parameters, all patients completed the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Autoquestionnaire (TEMPS-A) and the Beck Depression Inventory (BDI). Vascular age was estimated using coronary artery calcium (CAC) score and we calculated its difference from chronological age for each patient. Linear regression analysis was applied to identify predictors of early vascular aging in the entire cohort and in male and female sub-populations, separately.
Results: The independent predictors of early vascular aging were female sex (B = −10.82 [95% CI: −15.30 – −6.33]), diabetes mellitus (B = 7.16 [95% CI: 1.20 – 13.12]) and dyslipidemia (B = −8.28 [95% CI: 3.94 – 12.62]). Further assessing gender differences, cyclothymic temperament score proved to be an independent predictor of early vascular aging in women (B = 0.89 [95% CI: 0.04 – 1.75]), while this association was absent in men.
Conclusions: Our results suggest that cyclothymic affective temperament contribute to early vascular aging in women.
- © 2020 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
- Open Access
- This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - JOUR AU - Milan Vecsey-Nagy AU - Bálint Szilveszter AU - Márton Kolossváry AU - Xénia Gonda AU - Zoltán Rihmer AU - Béla Merkely AU - Pál Maurovich-Horvat AU - János Nemcsik PY - 2020 DA - 2020/12/31 TI - P.43 The Association Between Early Vascular Aging and Cyclothymic Affective Temperament JO - Artery Research SP - S65 EP - S65 VL - 26 IS - Supplement 1 SN - 1876-4401 UR - https://doi.org/10.2991/artres.k.201209.055 DO - 10.2991/artres.k.201209.055 ID - Vecsey-Nagy2020 ER -