Materials Highlights

In Press, Corrected Proof, Available Online: 18 January 2021

Review on Tympanic Membrane and Auditory Canal Regeneration by Biomaterial Intervention

Authors
Deepak Ranglani, Shubham Agiwal, Namdev More, Rohit Parkale, Vaibhav Shitole, Aishwarya Rajaram Hiray, Govinda Kapusetti*
Department of Medical Devices National Institute of Pharmaceutical Education and Research, Ahmedabad

Authors having equal contributions.

*Corresponding author. Email: govindphysics@gmail.com
Corresponding Author
Govinda Kapusetti
Received 14 June 2020, Accepted 16 December 2020, Available Online 18 January 2021.
DOI
https://doi.org/10.2991/mathi.k.201218.001How to use a DOI?
Keywords
Tympanic membrane, auditory canal, tissue engineering, biomaterials, cells, growth factors, stem cells
Abstract

The impairment in the Tympanic Membrane (TM) and the External Auditory Canal (EAC) results in otitis media, tympanos-clerosis, and perforations. The resulting reverberation of these pathologies is the loss of hearing, which eventually requires surgical treatment. The gold standard for the surgical procedures, autologous temporalis fascia, is reported with limited success. In recent times the biomaterial substitutes for this very purpose have carried off tremendous interest. The current review explicitly focuses on the last 10 years reports describing TM and EAC regeneration by biomaterial intervention. This review also provides an intelligible insight into various fabrication techniques for grafting to mimic TM-collagen’s radial and circular patterns. In the end, we have reached the terms by highlighting the future of the biomaterials in contrast to the current challenges in TM and EAC regeneration. Overall, the review will be a better source for developing futuristic biomaterials for the discussed problem.

Copyright
© 2021 The Authors. Published by Atlantis Press B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal
Materials Highlights
Publication Date
2021/01
ISSN (Online)
2666-4933
DOI
https://doi.org/10.2991/mathi.k.201218.001How to use a DOI?
Copyright
© 2021 The Authors. Published by Atlantis Press B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Deepak Ranglani
AU  - Shubham Agiwal
AU  - Namdev More
AU  - Rohit Parkale
AU  - Vaibhav Shitole
AU  - Aishwarya Rajaram Hiray
AU  - Govinda Kapusetti
PY  - 2021
DA  - 2021/01
TI  - Review on Tympanic Membrane and Auditory Canal Regeneration by Biomaterial Intervention
JO  - Materials Highlights
SN  - 2666-4933
UR  - https://doi.org/10.2991/mathi.k.201218.001
DO  - https://doi.org/10.2991/mathi.k.201218.001
ID  - Ranglani2021
ER  -