The Development and Bio-applications of Multifluid Electrospinning
Menglong Wang, Deng-Guang Yu, Xiaoyan Li, Gareth R Williams
Pages: 1 - 13
Electrospinning is a potent “top-down” nanofabrication method and has been explored by many researchers in recent decades because it is an efficient, versatile, simple, and low-cost route to prepare nanofibers. Nanofiber membranes generated by electrospinning have been used in various fields including...
Inkjet Printed Melatonin on Poly(vinyl alcohol) Oral Films: Uptake in an Ex Vivo Oral Mucosal Pellicle Model
Yin Ming Khor, Simon Gaisford, Guy Howard Carpenter, Bahijja Tolulope Raimi-Abraham
Pages: 1 - 6
There is a growing interest in the use of melatonin in preventing radiation-induced mucositis with potential beneficial effects including prevention of mucosal damage, the emergence of ulcers and the loss of proliferative progenitor stem cells caused by radiation. Local drug delivery to the oral cavity...
Review on Tympanic Membrane and Auditory Canal Regeneration by Biomaterial Intervention
Deepak Ranglani, Shubham Agiwal, Namdev More, Rohit Parkale, Vaibhav Shitole, Aishwarya Rajaram Hiray, Govinda Kapusetti
Pages: 7 - 17
The impairment in the Tympanic Membrane (TM) and the External Auditory Canal (EAC) results in otitis media, tympanos-clerosis, and perforations. The resulting reverberation of these pathologies is the loss of hearing, which eventually requires surgical treatment. The gold standard for the surgical procedures,...
Dual-stage Release of Ketoprofen from Electrosprayed Core–Shell Hybrid Polyvinyl Pyrrolidone/Ethyl Cellulose Nanoparticles
Pu Wang, Meng-long Wang, Xi Wan, Honglei Zhou, Heng Zhang, Deng-Guang Yu
Pages: 14 - 21
Dual-stage release, consisting of a first fast release for eliminating the uncomfortable symptoms and a later sustained release for a long time period for reducing the administration times, is highly welcomed by the patients. In the present investigation, a new type of core-shell Electrosprayed Nanoparticles...
Nanofabrication of Janus Fibers through Side-by-Side Electrospinning - A Mini Review
He Lv, Deng-Guang Yu, Menglong Wang, Tingbao Ning
Pages: 18 - 22
Janus and core–shell nanostructures are the most fundamental structural characteristics for comprising all types of multiple-chamber structures. The facile preparation of Janus structure is one of the most difficult challenges in the field of nanofabrication, whose production can pave a broad way for...
An Undergraduate Study for the Comparison of Dissolution Profiles using 3D Printed PVA and Commercial Paracetamol Tablets
Maryam Asmari, Bruno C. Sil, Bhaven Patel
Pages: 22 - 25
Structural and Optical Properties of BaO Nanoparticles Synthesized by Facile Co-precipitation Method
Manauwar Ali Ansari, Nusrat Jahan
Pages: 23 - 28
This paper presents the synthesis of Barium Oxide Nanoparticles (BaO-NPs) on a large-scale by a simple and cost-effective co-precipitation method. The as-synthesized BaO-NPs were characterized in aspects of their structural, morphological, compositional, and optical properties. X-ray diffraction was...
Bispecific Antibodies for the Treatment of Cancer
Pages: 29 - 40
Cancer is a devastating disease that can be challenging to treat. Fortunately, immune cells called T-cells can be activated for tumour destruction. Signal 1 of T-cell activation is provided by antigen presentation through the (T-cell receptor/major histocompatibility complex) interaction. Signal 2 of...
Conductive Inks with 3D Conductive Networks of Polyaniline Crystals Nanofibers
Dawei Li, Yulun Tao, Shun Yao, Wenxiang Tian, Guihui Wang, Baoyu Li, Wuji Wang, Shuo Li, Jinian Yang, Qingbo Yu, Shuxing Wu, Il Kim
Pages: 41 - 45
A series of Polyaniline (PANI) nanoparticles doped with citric acid were synthesized by situ polymerization. It is interesting that uniform nanofibers with the diameter of 50 nm formed under a proper mass ratio (aniline:citric acid) of 5:4, which forms 3D conductive networks. XRD patterns show the nanofibers...
Microstructure and Mechanical Properties of Cu–Al Alloy Deposited by Additive Manufacturing
Yanhu Wang, Sergey Konovalov, Xizhang Chen, Yurii Ivanov, R. Arvind Singh, S. Jayalakshmi, Xiaoming Pan
Pages: 46 - 51
In this work, Cu–4.9% Al alloy with little Si (the weight percentage is 1.3%) and little Mn (the weight percentage is 0.8%) was deposited by wire arc additive manufacturing. Microstructure and properties of the deposited alloy was investigated. Microstructural characterization was done using optical...
PVP-Induced Synthesis of Silica Nanoparticles with Tailored Size for pH-Controlled Drug Release
Wei Yang, Zheng Yang
Pages: 52 - 57
Traditional cancer therapy faces the main fail due to the effect of drug burst release, hindering the long-term therapeutic efficacy. SiO2 nano systems possess high-capacity and pH-controlled release for anti-cancer drug, improving the curative efficacy in cancer treatment. Thus, we designed a novel...
Recent Advances in Nanofabrication of the Morphology-Controlled Hypercrosslinked Polymers
Wenliang Song, Mingxin Zhang, Mingjie Liu, Yinning Huang, Dengguang Yu
Pages: 58 - 67
Hypercrosslinked Polymers (HCPs) have received considerable attention in the field of catalysis, adsorption, separation, biomedical engineering, and energy storage/conversion, because of their permanent microporous structures and high surface areas. Up to now, various “bottom-up” and “top-down” methods...
Nebulizer, Inhaled Remdesivir Nanoparticle Co-administered with Withania Somnifera may Minimize the Hepatotoxicity in COVID-19
R. Velmurugan, P. Manoj Kumar, Keerthi G.S. Nair
Pages: 68 - 70
Remdesivir is a broad spectrum antiviral agent meant to inhibit viral RNA polymerases against members of several virus families, including filoviruses. Although reported for significant clinical improvements in COVID-19, a detailed observation of the connection with the drawbacks of remdesivir therapy...