Simulations to Evaluate the Impact of Ca2+ release from Endoplasmic Reticulum on Intracellular Ca2+ Oscillations
Authors
Enlin Tang, Hongkun Zuo
Corresponding Author
Enlin Tang
Available Online November 2017.
- DOI
- 10.2991/amms-17.2017.47How to use a DOI?
- Keywords
- bifurcation; calcium oscillation; fast-slow dynamic analysis
- Abstract
The role of Ca2+ release from endoplasmic reticulum (ER) in influencing intracellular Ca2+ oscillation is elucidated. Various types of oscillations in a two-pool model are discussed, based on fast-slow dynamic analysis. Three types of burster are obtained by varying the parameter affecting Ca2+ release from ER, namely, subHopf-subHopf of point-cycle type, subHopf-cycle of point-cycle type with multiple rhythms and fold-fold of point-point type. The results may help us better understand the role of Ca2+ release played in complex intra- and inter-cellular Ca2+ signaling.
- Copyright
- © 2017, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Enlin Tang AU - Hongkun Zuo PY - 2017/11 DA - 2017/11 TI - Simulations to Evaluate the Impact of Ca2+ release from Endoplasmic Reticulum on Intracellular Ca2+ Oscillations BT - Proceedings of the 2017 International Conference on Applied Mathematics, Modeling and Simulation (AMMS 2017) PB - Atlantis Press SP - 211 EP - 214 SN - 1951-6851 UR - https://doi.org/10.2991/amms-17.2017.47 DO - 10.2991/amms-17.2017.47 ID - Tang2017/11 ER -