Proceedings of the 2016 International Conference on Biomedical and Biological Engineering

Influence of Daidzein and Daidzein Metabolites on Lifespan and Stress Resistance in Caenorhabditis Elegans

Authors
Ye Wang, Xiaolei Li, Conghui Zhang, Xiuling Wang
Corresponding Author
Ye Wang
Available Online July 2016.
DOI
https://doi.org/10.2991/bbe-16.2016.39How to use a DOI?
Keywords
Daidzein, Daidzein metabolites, C. elegans, Lifespan, Stress resistance
Abstract
Caenorhabditis elegans (C. elegans) was used as an animal model to study the influence of isoflavone daidzein and daidzein metabolites, including dihydrodaidzein (DHD), O-desmethylangolensin (O-Dma) and equol, on lifespan in C. elegans at the concentration of 0.1 mmol/L. The results showed that equol significantly increased the lifespan of C. elegans; however, O-Dma significantly shortened the lifespan of C. elegans. No obvious difference in lifespan was observed when the worms were exposed to daidzein and DHD, respectively. Further study on stress resistance demonstrated that both the thermal and oxidative stress tolerance capacity of C. elegans was significantly enhanced after being exposed to equol.
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This is an open access article distributed under the CC BY-NC license.

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Proceedings
International Conference on Biomedical and Biological Engineering
Part of series
Advances in Biological Sciences Research
Publication Date
July 2016
ISBN
978-94-6252-216-9
ISSN
2468-5747
DOI
https://doi.org/10.2991/bbe-16.2016.39How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Ye Wang
AU  - Xiaolei Li
AU  - Conghui Zhang
AU  - Xiuling Wang
PY  - 2016/07
DA  - 2016/07
TI  - Influence of Daidzein and Daidzein Metabolites on Lifespan and Stress Resistance in Caenorhabditis Elegans
BT  - International Conference on Biomedical and Biological Engineering
PB  - Atlantis Press
SN  - 2468-5747
UR  - https://doi.org/10.2991/bbe-16.2016.39
DO  - https://doi.org/10.2991/bbe-16.2016.39
ID  - Wang2016/07
ER  -