Proceedings of the 2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017)

Anticancer Activity of Oridonin Against Esophageal Cancer Cells Enhanced by Special Electromagnetic Field Treated Water

Authors
Jiang PI, Jin-huan JIANG, Hua JIN, Xin WANG, Yuan PENG, Ji-ye CAI
Corresponding Author
Jiang PI
Available Online May 2017.
DOI
https://doi.org/10.2991/bbe-17.2017.4How to use a DOI?
Keywords
Oridonin, Cancer, Special electromagnetic field treated water.
Abstract
Oridonin, the main pharmacological active substance isolated from Rabdosia Rubescens, has been found to show anti-inflammatory, pro-apoptotic, neurological effects, and excellent anticancer activities. However, the clinical application of oridonin is still limited by its poor solubility. The special electromagnetic field treated water (SEFT water) is served as a kind of high quality drinking water in China. In the present work, the SEFT water was used to test its effects on the anticancer activity of oridonin. And we found that the proliferation inhibition effects of oridonin in EC9706 cells were enhanced in SEFT water dissolved DMEM medium. And the apoptosis induction effects of oridonin in EC9706 cells were also enhanced in SEFT water dissolved DMEM medium, implying that SEFT water could enhance the anticancer effects of oridonin in cancer cells. It was also worth to note that the solubility of oridonin was also enhanced in SEFT water, which might contribute to the enhanced anticancer effects of oridonin in SEFT water dissolved medium for cancer cells.
Open Access
This is an open access article distributed under the CC BY-NC license.

Download article (PDF)

Proceedings
2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017)
Part of series
Advances in Biological Sciences Research
Publication Date
May 2017
ISBN
978-94-6252-362-3
ISSN
2468-5747
DOI
https://doi.org/10.2991/bbe-17.2017.4How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Jiang PI
AU  - Jin-huan JIANG
AU  - Hua JIN
AU  - Xin WANG
AU  - Yuan PENG
AU  - Ji-ye CAI
PY  - 2017/05
DA  - 2017/05
TI  - Anticancer Activity of Oridonin Against Esophageal Cancer Cells Enhanced by Special Electromagnetic Field Treated Water
BT  - 2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017)
PB  - Atlantis Press
SN  - 2468-5747
UR  - https://doi.org/10.2991/bbe-17.2017.4
DO  - https://doi.org/10.2991/bbe-17.2017.4
ID  - PI2017/05
ER  -