Proceedings of the 2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017)

Anti-Proliferative Activity of Benzamide Analogs in A549 Tumor Cells in Vitro

Authors
Li-wen SHEN, Yan-ling WU, Min CHEN, Yoshimasa Tanaka, Wen ZHANG
Corresponding Author
Li-wen SHEN
Available Online May 2017.
DOI
https://doi.org/10.2991/bbe-17.2017.32How to use a DOI?
Keywords
Anti-Proliferative, Benzamide Analogs, A549, RTCA.
Abstract
Objective: To determine the antitumor activity of five benzamide derivatives with similar structure in A549 tumor cells. Methods: Cytotoxicity of the compounds in A549 tumor cells were monitored through an xCELLigence Real-Time Cell Analysis System. Results: Four benzamide analogs inhibited the growth of A549 tumor cells in a dose- and time-dependent manner. Conclusion: Four benzamideÿderivatives exhibited antiproliferative activity against A549 tumor cells in vitro and could be further developed in preclinical studies as therapeutic agents for non small cell lung cancer.
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Proceedings
2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017)
Part of series
Advances in Biological Sciences Research
Publication Date
May 2017
ISBN
978-94-6252-362-3
ISSN
2468-5747
DOI
https://doi.org/10.2991/bbe-17.2017.32How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Li-wen SHEN
AU  - Yan-ling WU
AU  - Min CHEN
AU  - Yoshimasa Tanaka
AU  - Wen ZHANG
PY  - 2017/05
DA  - 2017/05
TI  - Anti-Proliferative Activity of Benzamide Analogs in A549 Tumor Cells in Vitro
BT  - 2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017)
PB  - Atlantis Press
SN  - 2468-5747
UR  - https://doi.org/10.2991/bbe-17.2017.32
DO  - https://doi.org/10.2991/bbe-17.2017.32
ID  - SHEN2017/05
ER  -