Anti-inflammatory and Angiotensin I-Converting Enzyme Inhibitory of Malvidin and its Glycosides from Vaccinium Ashei
- https://doi.org/10.2991/bst-17.2018.25How to use a DOI?
- Blueberry, Malvidin and glycosides, Anti-inflammation, ACE inhibitor, Endothelial cells.
Protective effects of malvidin and the glycosides from Vaccinium ashei on endothelial cells were investigated. The results showed that malvidin, malvidin-3-glucoside, malvidin-3-galactoside, and their mixture could defend endothelial cells from damage caused by TNF- , and inhibit monocyte chemotactic protein-1, intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and angiotensin I-converting enzyme expression. In addition, they could inhibit degradation of I B and obstruct the nuclear translocation of p65, suggesting the anti-inflammatory mechanism of NF- B pathway. The results indicated blueberry anthocyanins could be potential inflammation and ACE inhibitors, and blueberry could be functional foods advantageous to maintain a healthy cardiovascular population.
- © 2018, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Han Wu AU - Zheng Yan AU - Wu-Yang Huang PY - 2018/02 DA - 2018/02 TI - Anti-inflammatory and Angiotensin I-Converting Enzyme Inhibitory of Malvidin and its Glycosides from Vaccinium Ashei BT - Proceedings of the 2017 2nd International Conference on Biological Sciences and Technology (BST 2017) PB - Atlantis Press SP - 168 EP - 176 SN - 2468-5747 UR - https://doi.org/10.2991/bst-17.2018.25 DO - https://doi.org/10.2991/bst-17.2018.25 ID - Wu2018/02 ER -