Proceedings of the 3rd International Conference on Advances in Energy and Environmental Science 2015

Effects of Smoking on Rat Peptic Ulcer

Authors
Shu Jing, Wei Sun, Weihai Jiang
Corresponding Author
Shu Jing
Available Online July 2015.
DOI
10.2991/icaees-15.2015.118How to use a DOI?
Keywords
Smoking; Acetic acid; Gastric ulcer
Abstract

40 SD rats weighing 200 ± 10g were used, 12 of 40 rats were randomly selected as those in sham group, and the remaining 28 were used to establish the acetic acid-induced gastric ulcers to observe effects of smoking on the rat gastric ulcer and ulcer area. The acetic acid-induced gastric ulcer model in rats is reliable. Smoking can delay or the healing of ulcer, which may be related to the increase of gastric acid secretion induced by smoking, the increase in oxygen free radicals that can damage the mucosa of stomach, the decrease of pyloric sphincter tension, the reflux of bile and duodenal fluid to the stomach, and the reduction of prostaglandin E content in mucosa. It is recommended that in the treatment process of patients with gastric ulcer, they should stay away from smoking places, as much as possible avoid the hazards of passive smoking.

Copyright
© 2015, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Download article (PDF)

Volume Title
Proceedings of the 3rd International Conference on Advances in Energy and Environmental Science 2015
Series
Advances in Engineering Research
Publication Date
July 2015
ISBN
10.2991/icaees-15.2015.118
ISSN
2352-5401
DOI
10.2991/icaees-15.2015.118How to use a DOI?
Copyright
© 2015, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Shu Jing
AU  - Wei Sun
AU  - Weihai Jiang
PY  - 2015/07
DA  - 2015/07
TI  - Effects of Smoking on Rat Peptic Ulcer
BT  - Proceedings of the 3rd International Conference on Advances in Energy and Environmental Science 2015
PB  - Atlantis Press
SP  - 644
EP  - 647
SN  - 2352-5401
UR  - https://doi.org/10.2991/icaees-15.2015.118
DO  - 10.2991/icaees-15.2015.118
ID  - Jing2015/07
ER  -