Collagen Films with Extra Cellular Matrix via Combination of Supercritical Carbon Dioxide Fluid and NH4OH Treatments

DOI

10.2991/ice2me-19.2019.39How to use a DOI?

Keywords

ECM; NH4OH; SCF

Abstract

This study provide a new method for preparations of collagen films with extra cellular matrix via treatments of supercritical carbon dioxide fluid and NH4OH. Tissue engineering combines knowledge of engineering materials and medical applications to find more undiscovered things through this knowledge. Extracting bioactive collagen from the skin and bone of animals is a hot topic. A series of collagen scaffolds are obtained by removing the cell and subcutaneous fat from the porcine dermal via treatments of supercritical carbon dioxide fluid and NH4OH. The resulting collagen is mostly insoluble in water because of ECM structure. This study mainly focus on the effects of treatments of supercritical carbon dioxide fluid and ammonium solutions on the removal of subcutaneous fat and impurities from porcine dermal. Scanning electron microscope results showed the effect of supercritical fluid and aqueous ammonium solutions on preparations of collagen films with ECM by using porcine dermal tissue.

Copyright

© 2019, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Cong-Han Xiao
AU  - Ciao-Yi Syu
AU  - Yu-Lin Shen
AU  - Hsiao-Chih Hu
AU  - Meng-Jen Yang
AU  - Ing-Lin Chang
AU  - Ching-Cheng Huang
PY  - 2019/03
DA  - 2019/03
TI  - Collagen Films with Extra Cellular Matrix via Combination of Supercritical Carbon Dioxide Fluid and NH4OH Treatments
BT  - Proceedings of the 2019 International Conference on Electronical, Mechanical and Materials Engineering (ICE2ME 2019)
PB  - Atlantis Press
SP  - 174
EP  - 176
SN  - 2352-5401
UR  - https://doi.org/10.2991/ice2me-19.2019.39
DO  - 10.2991/ice2me-19.2019.39
ID  - Xiao2019/03
ER  -