Insertion Experiment and Resistance Tests of Solid Polymer Micro Needles Array

DOI

10.2991/iceep-18.2018.232How to use a DOI?

Keywords

Polymer micro-needle, Hot embossing, Taguchi method.

Abstract

Microneedles have been made from silicon, glass, and metal. Nowadays, many promising technologies are focused on polymers since they are biodegradable, biocompatible, and easy to fabricate. They can penetrate safely in the body, providing a drug distribution method and eliminating the risk of the needles fracturing and buckling. The problem faced by most transdermal patches is the low permeability of skin. Microneedles have been shown to greatly increase the skin's permeability, allowing for an effective transfer of drugs. They however still face numerous challenges. This work addresses the challenge to effectively microneedle insertion into porcine skin, which is similar to human skin. A 7x7 solid polymer microneedle array made by hot embossing process was tested for insertion. Results show that the array is extremely resistant to insertion, it can withstand very high forces and even multiple insertions without blunting.

Copyright

© 2018, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - S. Abubaker Samir
AU  - Yajun Zhang
AU  - Zhiming Jin
PY  - 2018/09
DA  - 2018/09
TI  - Insertion Experiment and Resistance Tests of Solid Polymer Micro Needles Array
BT  - Proceedings of the 2018 7th International Conference on Energy and Environmental Protection (ICEEP 2018)
PB  - Atlantis Press
SP  - 1322
EP  - 1326
SN  - 2352-5401
UR  - https://doi.org/10.2991/iceep-18.2018.232
DO  - 10.2991/iceep-18.2018.232
ID  - Samir2018/09
ER  -