Transgenerational Memory and piRNA

DOI

10.2991/assehr.k.211220.013How to use a DOI?

Keywords

Transgenerational memory; piRNA; fear-conditioning

Abstract

In this work, we got information from others’ papers that memory can be inherited by the next generation, and piRNA is associated with memory inheritance (according to Moore’s experiment). PiRNA is found present both in the nervous system and germ cells (according to Kandel’s paper) and associated with memory formation (according to Kandel’s article). Based on our research, we ask whether it is piRNA that causes memory inheritance. Then, the question comes, can the piRNA associated with the fear-conditioning neuronal circuit in a mouse’s brain migrate into their sperm cells? This work hypothesized that if the specific piRNA associated with the fear-conditioning neuronal circuit changes in abundance in the olfactory bulb, the sperm cells would be able to get these piRNA migrated from the brain region and thus inherit the memory of the odour used in the odour fear conditioning. The findings of the research may be applied to diseases prevention.

Copyright

© 2021 The Authors. Published by Atlantis Press SARL.

Open Access

This is an open access article under the CC BY-NC license.

Download article (PDF)

TY  - CONF
AU  - Xinyun Le
PY  - 2021
DA  - 2021/12/24
TI  - Transgenerational Memory and piRNA
BT  - Proceedings of the 2021 4th International Conference on Humanities Education and Social Sciences (ICHESS 2021)
PB  - Atlantis Press
SP  - 73
EP  - 77
SN  - 2352-5398
UR  - https://doi.org/10.2991/assehr.k.211220.013
DO  - 10.2991/assehr.k.211220.013
ID  - Le2021
ER  -