Immunological aspects of the use of L-carnitine in sports nutrition
Eleonora Trushina, Oksana Mustafina, Nikolay Riger
Available Online November 2019.
- https://doi.org/10.2991/icistis-19.2019.73How to use a DOI?
- sports nutrition, junior athletes, L-carnitine, immunity.
- The purpose of the work is to study the immunomodulating activity of L-carnitine in junior athletes during the training period. Materials and methods. 20 junior athletes (masters of sports and candidates for masters of sports in swimming) aged 14-18 years participated in the study. Athletes were divided into 2 groups of 10 people each. Athletes of the main group received L-carnitine (600 mg per day) for 4 weeks in addition to the basic diet. Athletes of the control group received only basic diet without sports nutrition. Examination of athletes was performed at the beginning and after 4 weeks of the observation period. Results. As a result of a comprehensive survey of junior athletes, the positive effect of L-carnitine intake on erythrocyte hemoglobin content (30.2 ± 0.4 pg vs 28.3 ± 0.3 pg at the beginning) was observed. The relative content of basophilic leukocytes in athletes of the main group statistically significantly decreased by the end of the observation period - from 0.64 ± 0.05% to 0.45 ± 0.04%, which indicated an increase in the body's resistance to allergic reactions. The biomarkers of the immunotropic effect of L-carnitine are a decrease in the expression of the apoptotic marker CD95/Fas on peripheral blood lymphocytes and suppression of the production of pro-inflammatory cytokines synthesized by Th1 lymphocytes with switching the response to humoral immunity. An evidence base for the effectiveness of the use of L-carnitine in sports nutrition for restoring immune dysfunction and adaptive potential of junior athletes has been provided.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
Cite this article
TY - CONF AU - Eleonora Trushina AU - Oksana Mustafina AU - Nikolay Riger PY - 2019/11 DA - 2019/11 TI - Immunological aspects of the use of L-carnitine in sports nutrition BT - Proceedings of the 4th International Conference on Innovations in Sports, Tourism and Instructional Science (ICISTIS 2019) PB - Atlantis Press SP - 288 EP - 290 SN - 2468-5739 UR - https://doi.org/10.2991/icistis-19.2019.73 DO - https://doi.org/10.2991/icistis-19.2019.73 ID - Trushina2019/11 ER -