Study on Silk/Carbamate Films
Hua Fu, Zhu-ping Yin, Feng Wu, Kai Liu, Shen-zhou Lu
Available Online February 2017.
- https://doi.org/10.2991/icmeim-17.2017.52How to use a DOI?
- Silk Fibroin,Carbamate,Blend Film,Cytocompatibility, Cornea Stroma Regeneration
- In this work, silk fibroin/carbamate blend films are fabricated in different ratios to improve the appropriate properties required for corneal stroma cell regeneration on the films. The structure of the films, the moisture content, protein dissolution loss rate, mechanical properties and light transmittance are investigated. The cytocompatibility of the films is tested with keratinocytes. The result shows that silk II crystalline structure in the film increases with the increase of carbamate content in the film. The light transmittance of the films is above 85%. The light transmittance at wet state is increased when the films are dipped in deionized water at room temperature for 24 hours. The tensile strength and elongation at break of the films are high enough for regeneration of corneal stroma cells both in dry and wet states. The blended films are able to support adhesion and proliferation of keratinocytes. This fibroin-carbamate blend films may offer an option for the corneal tissue engineering application.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
Cite this article
TY - CONF AU - Hua Fu AU - Zhu-ping Yin AU - Feng Wu AU - Kai Liu AU - Shen-zhou Lu PY - 2017/02 DA - 2017/02 TI - Study on Silk/Carbamate Films BT - 2017 International Conference on Manufacturing Engineering and Intelligent Materials (ICMEIM 2017) PB - Atlantis Press SP - 314 EP - 322 SN - 2352-5401 UR - https://doi.org/10.2991/icmeim-17.2017.52 DO - https://doi.org/10.2991/icmeim-17.2017.52 ID - Fu2017/02 ER -