Proliferation and Adhesion of Endothelial Cells on the Surface of Titanium Implant

DOI

10.2991/icmsa-15.2015.2How to use a DOI?

Keywords

Endothelial Cells, Dental Implants, Proliferation, Adhesion.

Abstract

To observe the proliferation and adhesion of umbilical cord endothelial cells (HUVEC) on the titanium (Ti) surface with large particles blasted-etched (SLA) treatments and further clarify the mechanism of action of each other between the Ti implant surface and the body. Methods: The human umbilical cord endothelial cells are cultured on the surface of SLA-Ti disks and culture plates. The proliferation of endothelial cells is detected by MTT method and adhesion of endothelial cells observed by PI fluorescence staining and western-bolt detection of protein of VE-cadherin. Results: The proliferation of endothelial cells on the titanium surface is better than the culture plate surfaces, the adhesion cells on titanium surface are more numbers, cell morphology is more extended, titanium surface expression of VE-cadherin protein higher than the culture plate surface. Conclusion: The SLA Ti surface can promote the proliferation and adhesion of endothelial cell and could promote the early healing process of osseointegration.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Jing-Ying Zhang
PY  - 2014/06
DA  - 2014/06
TI  - Proliferation and Adhesion of Endothelial Cells on the Surface of Titanium Implant
BT  - Proceedings of the 2015 International Conference on Material Science and Applications
PB  - Atlantis Press
SP  - 9
EP  - 13
SN  - 2352-541X
UR  - https://doi.org/10.2991/icmsa-15.2015.2
DO  - 10.2991/icmsa-15.2015.2
ID  - Zhang2014/06
ER  -