EFEKTIVENESS TEST OF AKAR KUCING PLANT EXTRACT (Acalypha indica Linn) TO LOWER TOTAL CHOLESTEROL LEVELS IN RATS (Rattus novergicus) WHICH INDUCED HYPERCHOLESTEROLEMIA DIET
- https://doi.org/10.2991/icpsuas-17.2018.79How to use a DOI?
- Acalypha indica Linn., total cholesterol, hypercholesterolemia
This research aims to determine the effect of ethanol extract of Acalypha indica Linn. on levels of total cholesterol of rat that is induced pig oil. This was an experimental research. The sample used was 20 rats were divided into 5 groups (1 group is consist of 4 rats), namely: 1) positive control, 2) negative control, 3) extract dose of 200 mg/kgBB, 4) extract dose of 400 mg/kgBB, 5) extract dose of 800 mg/kgBB. Group 2 to 5 are given pig oil as hypercholesterolemia diet, given for 28 days, then given treatment appropiate with the group. The result show that: 1) the average of total cholesterol levels increased after administration pork oil from 160 mg/dL to 232 mg/dL, 2) at a dose of 200 mg/kgBB, 400 mg/kgBB and 800 mg/kgBB showed a decline in total cholesterol levels by 189 mg/dl, 128 mg/dl, and 177 mg/dl. The result of this research concluse that Acalypha indica Linn. extract at dose of 200 mg/kgBB, 400 mg/kgBB and 800 mg kgBB have an effect in lowering total cholesterol of rat had been induced pork oil.
- © 2018, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Retno Sri Wahyuni AU - Fitria Agung Nugrahaningtyas AU - Nove Hidayati AU - Rochmah Kurnijasanti PY - 2017/08 DA - 2017/08 TI - EFEKTIVENESS TEST OF AKAR KUCING PLANT EXTRACT (Acalypha indica Linn) TO LOWER TOTAL CHOLESTEROL LEVELS IN RATS (Rattus novergicus) WHICH INDUCED HYPERCHOLESTEROLEMIA DIET BT - Proceedings of the 1st International Conference Postgraduate School Universitas Airlangga : "Implementation of Climate Change Agreement to Meet Sustainable Development Goals" (ICPSUAS 2017) PB - Atlantis Press SP - 365 EP - 367 SN - 2352-5398 UR - https://doi.org/10.2991/icpsuas-17.2018.79 DO - https://doi.org/10.2991/icpsuas-17.2018.79 ID - SriWahyuni2017/08 ER -