Association of Chlamydia trachomatis, Mycoplasma spp., Ureaplasma urealyticum and U. parvum with Human Papillomavirus in Patients with Cervical Cancer
- DOI
- 10.2991/absr.k.210810.003How to use a DOI?
- Keywords
- HPV, Cervical cancer, Chlamydia, Mycoplasma, Ureaplasma
- Abstract
Besides human papillomavirus (HPV), the cervical carcinogenesis is also affected by many risk factors including pathogenic bacteria such as Chlamydia trachomatis (CT), Mycoplasma spp. (MS), Ureaplasma urealyticum (UU), and U. parvum (UP) infections. Thus, we studied the bacterial infections for 68 patients with cervical cancerous cases and other cervical problems. Cervical swab samples were collected by specialist doctors and tested for the pathogenic bacteria by real time polymerase chain reaction (rPCR) and HPV by conventional PCR. Of 68 patients, 22 were diagnosed as cervical cancer and 46 were diagnosed as other cervical problems. All patients with cervical cancer were HPV positive, while the patients with other cervical problems were HPV negative. Of 22 HPV positive-cervical cancer patients, 7 (31.82%), 6 (27.27%), 3 (13.64%) were positive for MS, UU, and UP, respectively. None of the patients was CT positive. For 46 HPV negative-other cervical problem patients, 6 (13.04%), 12 (26.09%), 20 (43.48%), and 22 (47.83%) were positive for CT, MS, UU, and UP, respectively. There was no association of CT, MS, and UU infections with the HPV positive-cervical cancer patients (p >0.05). However, there is a negative correlation between UP infection and the HPV negative-other cervical problem patients (p<0.05).
- Copyright
- © 2021, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - A L Sahara AU - F Ibrahim AU - M N Massi AU - A Yasmon PY - 2021 DA - 2021/08/12 TI - Association of Chlamydia trachomatis, Mycoplasma spp., Ureaplasma urealyticum and U. parvum with Human Papillomavirus in Patients with Cervical Cancer BT - Proceedings of the 10th International Seminar and 12th Congress of Indonesian Society for Microbiology (ISISM 2019) PB - Atlantis Press SP - 12 EP - 17 SN - 2468-5747 UR - https://doi.org/10.2991/absr.k.210810.003 DO - 10.2991/absr.k.210810.003 ID - Sahara2021 ER -