Preparation of Lincomycin-β-Cyclodextrin Complex by Ultrasonic Method

DOI

10.2991/ism3e-15.2015.22How to use a DOI?

Abstract

To study the best process conditions for preparing ultrasonic lincomycin -cyclodextrin inclusion. Method: Choose the usage ration of Lincomycin hydrochloride with -cyclodextrin, the inclusion temperature and the time of reaction as the main factors, and use the inclusion yield as evaluated indicators and the process condition to conduct the L9 (34) orthogonal experiment Optimization Pack lincomycin hydrochloride. Outcome: The optimum inclusion process condition: molar ratio of the Lincomycin hydrochloride with -cyclodextrin is 1:3, inclusion temperature is 30 , inclusion time is 80 minutes. And use infrared spectrophotometry, microscopy imaging to identify the lincomycin hydrochloride -cyclodextrin inclusion complex has been formed.Conclusion: The process condition of using -cyclodextrin inclusion to inconcluse lincomycin hydrochloride is feasible, effective, and of applicative value.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Xiangqun Xu
AU  - Jie Yang
AU  - Youquan Zhong
AU  - Huayu Wang
AU  - Nian Hong
AU  - Lin Cheng
PY  - 2015/11
DA  - 2015/11
TI  - Preparation of Lincomycin-β-Cyclodextrin Complex by Ultrasonic Method
BT  - Proceedings of the 2015 International Symposium on Material, Energy and Environment Engineering
PB  - Atlantis Press
SP  - 81
EP  - 84
SN  - 2352-5401
UR  - https://doi.org/10.2991/ism3e-15.2015.22
DO  - 10.2991/ism3e-15.2015.22
ID  - Xu2015/11
ER  -