The Duration of Using ARV Therapy and the Incidence of Anemia in People Living with HIV/AIDS (PLWHA)

Siti Aisah; Dewi Setyawati; Ernawati Ernawati; Aulia Rima Rachmawati; Karina Megasari Winahyu; Abha Sharma

doi:10.2991/978-94-6463-132-6_12

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The Duration of Using ARV Therapy and the Incidence of Anemia in People Living with HIV/AIDS (PLWHA)

Authors

Siti Aisah¹, Dewi Setyawati¹^{, *}, Ernawati Ernawati¹, Aulia Rima Rachmawati¹, Karina Megasari Winahyu², Abha Sharma²

¹Department of Nursing, Faculty of Nursing and Health Sciences, Universitas Muhammadiyah Semarang, Semarang, Indonesia

²Faculty of Medicine, Ramathibodi Hospital and Faculty of Nursing, Mahidol University, Salaya, Thailand

^*Corresponding author. Email: dewisetyawati@unimus.ac.id

Corresponding Author

Dewi Setyawati

Available Online 19 April 2023.

DOI: 10.2991/978-94-6463-132-6_12 How to use a DOI?
Keywords: ARV; Anemia; HIV/AIDS
Abstract: Background: Anemia is a hematological complication that occurs in people living with HIV/AIDS (PLWHA). Anemia is multifactorial and can cause a decrease in the clinical condition and quality of life of PLWHA. Anemia that occurs in PLWHA can be influenced by the side effects of using Antiretroviral (ARV) therapy because ARV can inhibit the proliferation of red blood cells based on the duration of therapy. Azidothymidine (AZT) combinations are often associated with anemia, but previous studies have found the incidence of anemia in the Tenofovir Disoproxil Fumarate (TDF) combination as well.

Aim: The aim of this study is to find out the correlation between the duration of using ARV therapy based on a combination of AZT and TDF on the incidence of anemia in PLWHA.

Methods: The method of this study is a correlation analysis study with a retrospective method using secondary data, namely medical record data conducted at Public Health Center (Balai Kesehatan Masyarakat).

Results: This study found that 48% of PLWHA experienced anemia. Among them, 31.4% had mild anemia. The incidence of anemia was found to be higher (61.22%) in male. The incidence of anemia in this study was more common among AZT-combined ARV users as 54.4% of PLWHA using AZT experienced anemia. Further, this study found that 50% of PLWHA with ARV along with anti-TB treatment were anemic. All the PLWHA within 6–12 months of ARV therapy had anemia.

Conclusion: There was no significant correlation between duration of using ARV therapy based on a combination of AZT and TDF on the incidence of anemia in PLWHA.
Copyright: © 2023 The Author(s)
Open Access: Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title: Proceedings of the 1st Lawang Sewu International Symposium 2022 on Health Sciences (LSISHS 2022)
Series: Advances in Health Sciences Research
Publication Date: 19 April 2023
ISBN: 978-94-6463-132-6
ISSN: 2468-5739
DOI: 10.2991/978-94-6463-132-6_12 How to use a DOI?
Open Access: Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

ris enw bib

TY  - CONF
AU  - Siti Aisah
AU  - Dewi Setyawati
AU  - Ernawati Ernawati
AU  - Aulia Rima Rachmawati
AU  - Karina Megasari Winahyu
AU  - Abha Sharma
PY  - 2023
DA  - 2023/04/19
TI  - The Duration of Using ARV Therapy and the Incidence of Anemia in People Living with HIV/AIDS (PLWHA)
BT  - Proceedings of the 1st Lawang Sewu International Symposium 2022 on Health Sciences (LSISHS 2022)
PB  - Atlantis Press
SP  - 93
EP  - 102
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-132-6_12
DO  - 10.2991/978-94-6463-132-6_12
ID  - Aisah2023
ER  -

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