Proceedings of the 2015 International Conference on Materials Chemistry and Environmental Protection (meep-15)

Rosemary Extract Mediated Lifespan Extension in Drosophila Melanogaster

Authors
H.L. Wang, Z.S. Zhang, Z.O. Sun, H. Wang, N. Ma, H. Wang
Corresponding Author
H.L. Wang
Available Online March 2016.
DOI
https://doi.org/10.2991/meep-15.2016.49How to use a DOI?
Keywords
rosemary extract; drosophila melanogaster; anti-aging; antioxidation
Abstract
Rosemary (Rosmarinus officinalis L.) has always known a versatile, aromatic herb and addition to being used as a food flavoring is also known medicinally for its powerful antioxidant activity, antibacterial and hepatoprotective properties. In this study we examined the effects of rosemary iextract on the lifespan and aging in Drosophila melanogaster against high-fat induced oxidative injury, and found that it responded to rosemary extract with an increased lifespan and reduced MDA content during aging. We found that lifespan extension by rosemary extract was attributed to its increasing the activity of SOD, CAT and decreasing the content of MDA. Moreover, Realtime-PCR analysis showed that the gene expression of SOD, and CAT was enhanced, in contrast MTH was significantly reduced. In conclusion, these results suggest that the antioxidant and antiaging effect of rosemary extract may, at least in part, be due to its interactions with endogenous antioxidant protective enzymes including SOD and CAT.
Open Access
This is an open access article distributed under the CC BY-NC license.

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Proceedings
International Conference on Materials Chemistry and Environmental Protection 2015
Part of series
Advances in Physics Research
Publication Date
March 2016
ISBN
978-94-6252-169-8
ISSN
2352-541X
DOI
https://doi.org/10.2991/meep-15.2016.49How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - H.L. Wang
AU  - Z.S. Zhang
AU  - Z.O. Sun
AU  - H. Wang
AU  - N. Ma
AU  - H. Wang
PY  - 2016/03
DA  - 2016/03
TI  - Rosemary Extract Mediated Lifespan Extension in Drosophila Melanogaster
BT  - International Conference on Materials Chemistry and Environmental Protection 2015
PB  - Atlantis Press
SN  - 2352-541X
UR  - https://doi.org/10.2991/meep-15.2016.49
DO  - https://doi.org/10.2991/meep-15.2016.49
ID  - Wang2016/03
ER  -