Biological Function of CIRC-RNA and Its Role in Tumorigenesis

DOI

10.2991/meita-16.2017.105How to use a DOI?

Keywords

Circular RNA, Micro RNA Sponge, Tumor, Occurrence

Abstract

Over the years, with advances in RNA research, researchers have found not only the large number of circular RNAs found in many organisms, but also their important biological functions. Cyclic RNA is derived from introns or exons, can act as a micro RNA sponge, but also with the protein combination to participate in the regulation of gene expression and affect the function of the protein, in addition to individual circular RNA even can encode the protein. More importantly, cyclic RNA in tumor (such as: gastric cancer, liver cancer, colorectal cancer, breast cancer, cervical cancer and ovarian cancer, etc.) play an important role in the process of development and regulation. Therefore, the circular RNA is expected to become a tumor marker and a new target for treatment.

Copyright

© 2017, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Jialin Guo
AU  - Xiaozhi Yang
PY  - 2017/02
DA  - 2017/02
TI  - Biological Function of CIRC-RNA and Its Role in Tumorigenesis
BT  - Proceedings of the 2016 2nd International Conference on Materials Engineering and Information Technology Applications (MEITA 2016)
PB  - Atlantis Press
SP  - 503
EP  - 508
SN  - 2352-5401
UR  - https://doi.org/10.2991/meita-16.2017.105
DO  - 10.2991/meita-16.2017.105
ID  - Guo2017/02
ER  -