Anti-obesity effect of the jasminum sambac (l.) W.ait. Ethanol extract in high fat diet induced mice
- DOI
- 10.2991/smichs-17.2017.43How to use a DOI?
- Keywords
- Ethanol extract, High-fat diet, Jasminum sambac, Obesity
- Abstract
Objective:. The aim of this research is to identify the potential anti-obesity effect of Jasminum sambac (L.) W.Ait. ethanol extract in high-fat-diet-induced mice. Method: This assay was administered to high-fat diet induced mice for 30 days, to get an increase of body weight of 20% higher than early body weight. After induction, obese mice groups were treated using Jasminum sambac (L.) W.Ait. ethanol extract at the dose 100, 300, 500 mg/kg BW and orlistat 23 mg/kg BW as standard drug. To determine the anti-obesity effect, measurements were conducted by daily weight, food index, feces index, urine index, and stool consistency. The data were statistically analyzed by One-Way ANOVA followed by LSD test (Least Significant Different). Results: The experiment showed that Jasminum sambac (L.) W.Ait. extract dose of 100, 300, 500 mg/kg BW induced a high-fat diet indicated a significant decrease in body weight, fat index and organs index compared to control mice. Conclusion: The best dose decrease in body weight in the dose of 100 mg/kg BW and the best dose of reduced fat and organ weight in the dose of 300 mg/kg BW.
- Copyright
- © 2017, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Muhammad Ramadhan AU - Ari Yuniarto AU - Ika Kurnia S PY - 2017/12 DA - 2017/12 TI - Anti-obesity effect of the jasminum sambac (l.) W.ait. Ethanol extract in high fat diet induced mice BT - Proceedings of the 2nd Sari Mulia International Conference on Health and Sciences 2017 (SMICHS 2017) PB - Atlantis Press SP - 351 EP - 358 SN - 2468-5739 UR - https://doi.org/10.2991/smichs-17.2017.43 DO - 10.2991/smichs-17.2017.43 ID - Ramadhan2017/12 ER -