Proceedings of the 2nd Sari Mulia International Conference on Health and Sciences 2017 (SMICHS 2017)

Antipyretic Effects of (phaleria macrocarpa (scheff) boerl.) Infusa In Mice Galur Wistar As Animal Model

Authors
Noval Noval, Ali Rakhman Hakim, Ahmad Irawan
Corresponding Author
Noval Noval
Available Online December 2017.
DOI
10.2991/smichs-17.2017.44How to use a DOI?
Keywords
Antipyretic Effects, Mice Galur Wistar, Phaleria Macrocarpa (Scheff) Boerl
Abstract

Objective: This study was conducted to prove the antipyretic effect of the (Phaleria Macrocarpa (Scheff) Boerl.) and the effect strength, because the scientific evidence and its benefits were still limited, although empirically its leaf has been widely used by society as antipyretics.Methods: Measurements were performed prior to condensation solution until after the solvent solution was performed at minute 0, 30, 60, 90, 120, and 180. The presence of antipyretic effect was indicated by a statistically significant different down temperature between the test groups and the positive control group. Statistical analysis using ANOVA (Analysis of Variance) and LSD (Least Significant Different) Test. Results: Results at concentrations of 3% showed a decrease in body temperature actively different against positive controls at 60, 120 and 180 (p <0.05), at a concentration of 6% showing a decrease in body temperature to positive controls at 120 and 180 minutes (P <0.05), whereas at a concentration of 12% showed a decrease in body temperature was actively different against positive controls at 30, 60, 120 and 180 (p <0.05). Conclusion: A 12% concentration showed the best antipyretic activity with the faster onset of action and the longest duration of action.

Copyright
© 2017, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2nd Sari Mulia International Conference on Health and Sciences 2017 (SMICHS 2017)
Series
Advances in Health Sciences Research
Publication Date
December 2017
ISBN
978-94-6252-468-2
ISSN
2468-5739
DOI
10.2991/smichs-17.2017.44How to use a DOI?
Copyright
© 2017, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Noval Noval
AU  - Ali Rakhman Hakim
AU  - Ahmad Irawan
PY  - 2017/12
DA  - 2017/12
TI  - Antipyretic Effects of (phaleria macrocarpa (scheff) boerl.) Infusa In Mice Galur Wistar As Animal Model
BT  - Proceedings of the 2nd Sari Mulia International Conference on Health and Sciences 2017 (SMICHS 2017)
PB  - Atlantis Press
SP  - 359
EP  - 368
SN  - 2468-5739
UR  - https://doi.org/10.2991/smichs-17.2017.44
DO  - 10.2991/smichs-17.2017.44
ID  - Noval2017/12
ER  -