Changes in the State of Cell Membranes of an Animal Organism Against the background of the Protective Effect of Antioxidants Under Conditions of High Temperature
Elena Nechaeva, Olga Bdyukhina, Tatyana Mitsulya
Available Online 29 January 2020.
- https://doi.org/10.2991/assehr.k.200113.155How to use a DOI?
- hyperthermia, erythrocytes, leucocytes, lipid peroxidation, antioxidants
- The morphological and functional condition of biological membranes of cells and their resistance while exposed to high temperature of 41° C for 180 minutes were studied in this research. The damaging effect of exogenous hyperthermic pressure was corrected by the preliminary administration of antioxidants unitiol and à-tocopherol. Malondialdehyde in blood serum was researched as the content of the final product of lipid peroxidation. Indicators of blood cell resistance of experimental animals were evaluated. The osmotic resistance of leukocytes and erythrocytes, the indicatos of permeability of erythrocyte membranes, the level of peroxide hemolysis of red blood cells, the number and speed of urea hemolysis of red blood cells were studied. It was discovered that acute experimental hyperthermia causes activation of the process of formation of peroxide radicals. Significant changes occur in the processes associated with the compensation of free radical oxidation. The preliminary injections of antioxidant agents - unitiol and α-tocopherol - given to experimental animals, reduces the negative outcomes of the damaging effects of hyperthermia and has a pronounced normalizing effect.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
Cite this article
TY - CONF AU - Elena Nechaeva AU - Olga Bdyukhina AU - Tatyana Mitsulya PY - 2020 DA - 2020/01/29 TI - Changes in the State of Cell Membranes of an Animal Organism Against the background of the Protective Effect of Antioxidants Under Conditions of High Temperature BT - Proceedings of the International Scientific Conference The Fifth Technological Order: Prospects for the Development and Modernization of the Russian Agro-Industrial Sector (TFTS 2019) PB - Atlantis Press SP - 135 EP - 140 SN - 2352-5398 UR - https://doi.org/10.2991/assehr.k.200113.155 DO - https://doi.org/10.2991/assehr.k.200113.155 ID - Nechaeva2020 ER -