Proceedings of the International Scientific Conference The Fifth Technological Order: Prospects for the Development and Modernization of the Russian Agro-Industrial Sector (TFTS 2019)

Changes in the State of Cell Membranes of an Animal Organism Against the background of the Protective Effect of Antioxidants Under Conditions of High Temperature

Authors
Elena Nechaeva, Olga Bdyukhina, Tatyana Mitsulya
Corresponding Author
Elena Nechaeva
Available Online 29 January 2020.
DOI
https://doi.org/10.2991/assehr.k.200113.155How to use a DOI?
Keywords
hyperthermia, erythrocytes, leucocytes, lipid peroxidation, antioxidants
Abstract
The morphological and functional condition of biological membranes of cells and their resistance while exposed to high temperature of 41° C for 180 minutes were studied in this research. The damaging effect of exogenous hyperthermic pressure was corrected by the preliminary administration of antioxidants unitiol and à-tocopherol. Malondialdehyde in blood serum was researched as the content of the final product of lipid peroxidation. Indicators of blood cell resistance of experimental animals were evaluated. The osmotic resistance of leukocytes and erythrocytes, the indicatos of permeability of erythrocyte membranes, the level of peroxide hemolysis of red blood cells, the number and speed of urea hemolysis of red blood cells were studied. It was discovered that acute experimental hyperthermia causes activation of the process of formation of peroxide radicals. Significant changes occur in the processes associated with the compensation of free radical oxidation. The preliminary injections of antioxidant agents - unitiol and α-tocopherol - given to experimental animals, reduces the negative outcomes of the damaging effects of hyperthermia and has a pronounced normalizing effect.
Open Access
This is an open access article distributed under the CC BY-NC license.

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Cite this article

TY  - CONF
AU  - Elena Nechaeva
AU  - Olga Bdyukhina
AU  - Tatyana Mitsulya
PY  - 2020
DA  - 2020/01/29
TI  - Changes in the State of Cell Membranes of an Animal Organism Against the background of the Protective Effect of Antioxidants Under Conditions of High Temperature
BT  - Proceedings of the International Scientific Conference The Fifth Technological Order: Prospects for the Development and Modernization of the Russian Agro-Industrial Sector (TFTS 2019)
PB  - Atlantis Press
SP  - 135
EP  - 140
SN  - 2352-5398
UR  - https://doi.org/10.2991/assehr.k.200113.155
DO  - https://doi.org/10.2991/assehr.k.200113.155
ID  - Nechaeva2020
ER  -