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The Programmed Cell Death 1 (PD-1)/Programmed Death Ligand 1 (PD-L1) Immune Checkpoint Inhibitors (ICIs), have become a hot spot in the field of cancer research and treatment, and bring new hope to patients with advanced tumors. But, in addition to enhancing the anti-tumor effect of T cells, PD-1/PD-L1...

Nowadays many regions are faced with competition to attract tourists, in-vestments, and residents as well as many other purposes that could drive the development of the region. It is considered important for a region to have identity as differentiatior from other regions that could become the direction...

Competition in 21st-century society is very tight. To survive the competition that occurs, there is a solution to develop: financial literacy. Indonesia is one of the countries that are relatively low on financial literacy com-pared to other countries, according to The World Bank survey results in 2015....

Sepsis caused by Staphylococcus aureus disrupts hematologic, metabolic, and immune functions. Zinc and vitamin E, with antioxidant and immunomodulatory properties, may mitigate these effects. Thirty male Wistar rats aged 12 to 16 weeks and weighing 150 to 200 grams were randomized into six groups of...

Age and hypertension are major causes of large artery stiffening, a cardiovascular risk factor for heart and kidney damage. Long term hypertension induces vascular remodeling, accelerating vascular aging. The aged Spontaneously Hypertensive Rat (SHR) model is recognized for human cardiovascular pathology...

This design aims to develop a PLC and HMI application in the scope of automation in the automotive industry. The implementation of the fuel selector switch function was made as a simple project for a control system related to the use of fuel in a bi-fuel SI engine that operates with gasoline or LPG....

Hiperglikemia in Type 2 Diabetes Mellitus (DM) have an impact on increasing the coagulation activity of the human homeostatic system. DM is a comorbidity of stroke. An increase of Platelet Count (PC) and Mean Platelet Volume (MPV) is useful for assessing the prognosis and severity of ischemic stroke....

In this study, the therapeutic effect of a novel human parathyroid hormone analogs nasal drops on ovariectomized rats was evaluated. Thirty-two of 40 3-month-old female Sprague-Dawley rats were ovariectomized and 8 received sham operation. Thirteen weeks later, ovariectomized rats were randomly and averagely...

Background: Incretine hormone glucagon-like peptide-1 (GLP-1) causes dose-dependent relaxation of the thoracic aorta of rats and other arteries via nitric oxide (NO), cAMP and ATP-sensitive potassium channels, however, through a mechanism not thoroughly described. Hereby we aimed to determine the mediators...

Salt poisoning could be important for the pets’ life. High salt and low water consumptions can be effective in the formation of salt poisoning. Low levels of salt poisoning increase blood pressure which reduces the quality of life. Plant-origin cat and dog liquid additives are previously used and improve...

Burn is still an important problem in health facility worldwide. Burns management from ancients ago until now is quite varied either giving topical therapy alone or combination with systemic drug along with various clinical considerations. Research on the healing of burns with phytoextract has been done...