eFood

Volume 1, Issue 1, February 2020, Pages 61 - 68

Twenty-four Months Feeding on Unsaturated Dietary Fats (Virgin Olive, Sunflower, or Fish Oil) Differentially Modulate Gingival Mitochondria in the Rat

Authors
María D. Navarro-Hortal1, Alfonso Varela-López1, José M. Romero-Márquez1, Celia Piquer-Martinez1, Pedro Bullón2, Tamara Y. Forbes-Hernández3, José L. Quiles1, *
1Department of Physiology, Biomedical Research Center, Institute of Nutrition and Food Technology “José Mataix Verdú”, University of Granada, Avda del Conocimiento sn., Armilla, Granada 18100, Spain
2Department of Oral Medicine and Periodontology, University of Seville, Sevilla, Spain
3Nutrition and Food Science Group, Department of Analytical and Food Chemistry, CITACA, CACTI, University of Vigo, Vigo, Spain
*Corresponding author. Email: jlquiles@ugr.es
Corresponding Author
José L. Quiles
Received 18 July 2019, Accepted 29 July 2019, Available Online 23 August 2019.
DOI
https://doi.org/10.2991/efood.k.190802.002How to use a DOI?
Keywords
Aging; fatty acids; gene expression; biogenesis; autophagy; apoptosis
Abstract

This study investigated the effects of feeding rats for 24 months on different unsaturated fats (virgin olive, sunflower, or fish oil) on gingival mitochondrial ultrastructure and expression of genes related to mitochondrial biology as well as the amount of circulating fatty acids in the plasma. Results show that sunflower oil led to a higher mitochondrial area, perimeter, and area:perimeter ratio, markers of swelling, and increased age. Sunflower oil also led to increased gene expression associated to biogenesis, autophagy, oxidative stress, and apoptosis. Genes related to mitochondrial electron chain did not result affected by treatments. As old rats lifelong fed on sunflower oil have previously showed higher alveolar bone resorption, a major feature of periodontitis, we could conclude that age-related alveolar bone resorption associated with n6PUFA would be, at least in part, mediated by changes in mitochondrial ultrastructure and gene expression at the gingival tissue.

Copyright
© 2019 International Association of Dietetic Nutrition and Safety. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal
eFood
Volume-Issue
1 - 1
Pages
61 - 68
Publication Date
2019/08/23
ISSN (Online)
2666-3066
DOI
https://doi.org/10.2991/efood.k.190802.002How to use a DOI?
Copyright
© 2019 International Association of Dietetic Nutrition and Safety. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - María D. Navarro-Hortal
AU  - Alfonso Varela-López
AU  - José M. Romero-Márquez
AU  - Celia Piquer-Martinez
AU  - Pedro Bullón
AU  - Tamara Y. Forbes-Hernández
AU  - José L. Quiles
PY  - 2019
DA  - 2019/08/23
TI  - Twenty-four Months Feeding on Unsaturated Dietary Fats (Virgin Olive, Sunflower, or Fish Oil) Differentially Modulate Gingival Mitochondria in the Rat
JO  - eFood
SP  - 61
EP  - 68
VL  - 1
IS  - 1
SN  - 2666-3066
UR  - https://doi.org/10.2991/efood.k.190802.002
DO  - https://doi.org/10.2991/efood.k.190802.002
ID  - Navarro-Hortal2019
ER  -