In Vivo Antitumor Activity of Meretrix meretrix Glycopeptide

DOI

10.2991/asei-15.2015.425How to use a DOI?

Keywords

Xenografted tumor, Ehrlich's ascitic carcinoma, Hepatocellular carcinoma, Immunopotentiation

Abstract

MGP0501, one low-molecular-weight glycopeptide extracted from the sea mollusk Meretrix meretri, was investigated in this study for its effects on the growth of the tumor tissue and immune organs in xenografted sarcoma 180(S180), Ehrlich's ascitic carcinoma (EAC) and Hepatocellular carcinoma (Heps). Cyclophosphamide was choose as the comparator for the immunologic function analysis. The results indicate that MGP0501 has not only treatment effect on S180, EAC and Heps but also immunopotentiation effect on S180, suggesting MGP0501 has a stable and broad spectrum antitumor activity.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Jielian Wu
AU  - Shan Xu
PY  - 2015/05
DA  - 2015/05
TI  - In Vivo Antitumor Activity of Meretrix meretrix Glycopeptide
BT  - Proceedings of the 2015 International conference on Applied Science and Engineering Innovation
PB  - Atlantis Press
SP  - 2162
EP  - 2166
SN  - 2352-5401
UR  - https://doi.org/10.2991/asei-15.2015.425
DO  - 10.2991/asei-15.2015.425
ID  - Wu2015/05
ER  -