Proceedings of the 2015 International conference on Applied Science and Engineering Innovation

Synthesis of 6-bromo-4-iodoquinoline

Authors
Wenhui Wang, Yuping Guo, Linxiao Wang, Yiqiang OuYang, Qinqin Wang, Wufu Zhu
Corresponding Author
Wenhui Wang
Available Online May 2015.
DOI
10.2991/asei-15.2015.424How to use a DOI?
Keywords
Synthesis, 4-Bromoaniline, 6-bromo-4-iodoquinoline
Abstract

6-Bromo-4-iodoquinoline is an important intermediate for the synthesis of many biologically active compounds, such as GSK2126458. It was synthesized from 2,2-dimethyl-1,3- dioxane-4,6-dione and 4-bromoaniline through five steps including cyclization reaction and substitution reaction. And the structures of 6-bromoquinolin-4-ol and 6-bromo-4-iodoquinoline were confirmed by 1H NMR spectrum.

Copyright
© 2015, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2015 International conference on Applied Science and Engineering Innovation
Series
Advances in Engineering Research
Publication Date
May 2015
ISBN
10.2991/asei-15.2015.424
ISSN
2352-5401
DOI
10.2991/asei-15.2015.424How to use a DOI?
Copyright
© 2015, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Wenhui Wang
AU  - Yuping Guo
AU  - Linxiao Wang
AU  - Yiqiang OuYang
AU  - Qinqin Wang
AU  - Wufu Zhu
PY  - 2015/05
DA  - 2015/05
TI  - Synthesis of 6-bromo-4-iodoquinoline
BT  - Proceedings of the 2015 International conference on Applied Science and Engineering Innovation
PB  - Atlantis Press
SP  - 2158
EP  - 2161
SN  - 2352-5401
UR  - https://doi.org/10.2991/asei-15.2015.424
DO  - 10.2991/asei-15.2015.424
ID  - Wang2015/05
ER  -