Synthesis of 6-bromo-4-iodoquinoline
- 10.2991/asei-15.2015.424How to use a DOI?
- Synthesis, 4-Bromoaniline, 6-bromo-4-iodoquinoline
6-Bromo-4-iodoquinoline is an important intermediate for the synthesis of many biologically active compounds, such as GSK2126458. It was synthesized from 2,2-dimethyl-1,3- dioxane-4,6-dione and 4-bromoaniline through five steps including cyclization reaction and substitution reaction. And the structures of 6-bromoquinolin-4-ol and 6-bromo-4-iodoquinoline were confirmed by 1H NMR spectrum.
- © 2015, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Wenhui Wang AU - Yuping Guo AU - Linxiao Wang AU - Yiqiang OuYang AU - Qinqin Wang AU - Wufu Zhu PY - 2015/05 DA - 2015/05 TI - Synthesis of 6-bromo-4-iodoquinoline BT - Proceedings of the 2015 International conference on Applied Science and Engineering Innovation PB - Atlantis Press SP - 2158 EP - 2161 SN - 2352-5401 UR - https://doi.org/10.2991/asei-15.2015.424 DO - 10.2991/asei-15.2015.424 ID - Wang2015/05 ER -