Proceedings of the 2016 International Conference on Biological Sciences and Technology

Preparation of Diuridine and Dicytidine Pentaphosphates

Authors
Yue-Hai You, Shan-Shan Gong, Qi Sun
Corresponding Author
Yue-Hai You
Available Online January 2016.
DOI
https://doi.org/10.2991/bst-16.2016.11How to use a DOI?
Keywords
Phosphoropiperidate, Dinucleoside pentaphosphates, Cytidine, Uridine, 4,5-dicyanoimidazole.
Abstract
Two symmetrical dinucleoside pentaphosphates, Up5U and Cp5C, were synthesized via the activation of the P (V)–N bond. The key nucleoside phosphoropiperidates intermediate were obtained by a redox condensation method. The reaction of the phosphoropiperidate with uridine and cytidine tetraphosphate in the presence of 4, 5-dicyanoimidazole (DCI) afforded the desired dinucleoside pentaphosphates in moderate isolated yields.
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Proceedings
The International Conference on Biological Sciences and Technology
Part of series
Advances in Biological Sciences Research
Publication Date
January 2016
ISBN
978-94-6252-161-2
ISSN
2468-5747
DOI
https://doi.org/10.2991/bst-16.2016.11How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Yue-Hai You
AU  - Shan-Shan Gong
AU  - Qi Sun
PY  - 2016/01
DA  - 2016/01
TI  - Preparation of Diuridine and Dicytidine Pentaphosphates
BT  - The International Conference on Biological Sciences and Technology
PB  - Atlantis Press
SN  - 2468-5747
UR  - https://doi.org/10.2991/bst-16.2016.11
DO  - https://doi.org/10.2991/bst-16.2016.11
ID  - You2016/01
ER  -