Synthesis of 4-(4-aminophenoxy)-N-propylpicolinamide

DOI

10.2991/bst-17.2018.36How to use a DOI?

Keywords

4-(4-aminophenoxy)-N-propylpicolinamide, Synthesis.

Abstract

4-(4-aminophenoxy)-N-propylpicoliamide 4 is an important intermediate for the synthesis of many biologically active compounds. The compound 4-(4-aminophenoxy)-N-propylpicolinamide was obtained by three simple steps to synthesis from picolinic acid. In this paper, three novel 3-phenyl-1H-pyrazole derivatives were prepared. The structure was confirmed by MS and 1H NMR. Furthermore, the synthetic method was optimized. The total yield of the target product was 80%.

Copyright

© 2018, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Download article (PDF)

TY  - CONF
AU  - He-Hua Xiong
AU  - Jia Zhi
AU  - Yin-Mei Zhuang
AU  - Meng-Zi Chen
AU  - Yin-Hua Xiong
AU  - Qi-Dong Tang
PY  - 2018/02
DA  - 2018/02
TI  - Synthesis of 4-(4-aminophenoxy)-N-propylpicolinamide
BT  - Proceedings of the 2017 2nd International Conference on Biological Sciences and Technology (BST 2017)
PB  - Atlantis Press
SP  - 243
EP  - 246
SN  - 2468-5747
UR  - https://doi.org/10.2991/bst-17.2018.36
DO  - 10.2991/bst-17.2018.36
ID  - Xiong2018/02
ER  -