Differences of Salivary Superoxide Dismutase Levels in Gingivitis and Periodontitis Patients: Periodontal Installation, Faculty Of Dentistry, Universitas Sumatera Utara
- https://doi.org/10.2991/idsm-17.2018.37How to use a DOI?
- saliva, superoxide dismutase, antioxidant, gingivitis, periodontitis,
Introduction: Periodontal disease can be divided into gingivitis and periodontitis. In oral tissue, polymorphonuclear leukocytes (PMNs) are the first defense against pathogenic microorganisms. Activated PMNs produce large amounts of reactive oxygen species (ROS) that cause the destruction of periodontal tissue via various mechanisms and oxidative stress. Hosts are able to release antioxidants to elimi-nate ROS; one of the most effective antioxidants is superoxide dismutase (SOD). Previous studies have suggested that antioxidant levels, including SOD, are higher for periodontitis than for gingivitis or healthy people. In contrast, previous re-search has also found that levels of antioxidants, including SOD, were higher in healthy people followed by gingivitis and then periodontitis. Objectives: The pur-pose of this study was to determine differences in salivary SOD levels in patients with gingivitis and periodontitis. Methods: This was an analytic study with a cross-sectional design. There were 44 subjects:22 with gingivitis and 22 with periodonti-tis recruited from the periodontal installation of the Dentistry Faculty, University of Sumatera Utara, Medan, Indonesia. All subjects’ periodontal tissues were ex-amined to determine their periodontal status. Subjects were sampled by collecting 2 ml of saliva and salivary SOD levels were measured using a spectrophotometer. The data was analysed using an independent t-test. Result: The results showed a significant difference (p<0.05) between salivary SOD levels of gingivitis patients (12.44±4.43, p=0.377) and periodontitis patients (9.19±3.74, p=0.228). Conclu-sion: Salivary SOD levels were higher in patients with gingivitis than for patients with periodontitis.
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TY - CONF AU - Armia Syahputra AU - Krisnamurthy Krisnamurthy AU - Chrisnawati Sinaga PY - 2018/05 DA - 2018/05 TI - Differences of Salivary Superoxide Dismutase Levels in Gingivitis and Periodontitis Patients: Periodontal Installation, Faculty Of Dentistry, Universitas Sumatera Utara BT - Proceedings of the 11th International Dentistry Scientific Meeting (IDSM 2017) PB - Atlantis Press SP - 273 EP - 279 SN - 2468-5739 UR - https://doi.org/10.2991/idsm-17.2018.37 DO - https://doi.org/10.2991/idsm-17.2018.37 ID - Syahputra2018/05 ER -